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58932-30-2

2-(2-aminoethoxy)benzamide, also known as Benzamide, 2-(2-aminoethoxy)or 2-(2-Aminoethoxy)benzoic acid amide, is a chemical compound with the molecular formula C9H12N2O2. It is a benzamide derivative featuring an aminoethoxy substituent, which contributes to its unique chemical and biological properties. 2-(2-aminoethoxy)benzamide is utilized in various research and industrial applications, predominantly as a building block in the synthesis of pharmaceuticals and other organic compounds. The specific properties and uses of 2-(2-aminoethoxy)benzamide are contingent upon the context and application in which it is employed.

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  • 58932-30-2 Structure

  • Basic information

    1. Product Name: 2-(2-aminoethoxy)benzamide
    2. Synonyms: 2-(2-aminoethoxy)benzamide;2-(2-Aminoethoxy)
    3. CAS NO:58932-30-2
    4. Molecular Formula: C9H12N2O2
    5. Molecular Weight: 180.20378
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 58932-30-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 366.8°C at 760 mmHg
    3. Flash Point: 202.2°C
    4. Appearance: /
    5. Density: 1.183g/cm3
    6. Vapor Pressure: 1.43E-05mmHg at 25°C
    7. Refractive Index: 1.57
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 15.59±0.50(Predicted)
    11. CAS DataBase Reference: 2-(2-aminoethoxy)benzamide(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-(2-aminoethoxy)benzamide(58932-30-2)
    13. EPA Substance Registry System: 2-(2-aminoethoxy)benzamide(58932-30-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 58932-30-2(Hazardous Substances Data)

58932-30-2 Usage

Uses

Used in Pharmaceutical Synthesis:
2-(2-aminoethoxy)benzamide is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex molecular structures, potentially enhancing the therapeutic efficacy of the resulting compounds.
Used in Organic Chemistry Research:
In the field of organic chemistry, 2-(2-aminoethoxy)benzamide serves as a valuable research tool, enabling scientists to explore novel chemical reactions and mechanisms involving benzamide derivatives.
Used in Chemical Synthesis Industry:
2-(2-aminoethoxy)benzamide is utilized as a building block in the chemical synthesis industry, contributing to the creation of a wide range of organic compounds with diverse applications, from specialty chemicals to advanced materials.

Check Digit Verification of cas no

The CAS Registry Mumber 58932-30-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,9,3 and 2 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 58932-30:
(7*5)+(6*8)+(5*9)+(4*3)+(3*2)+(2*3)+(1*0)=152
152 % 10 = 2
So 58932-30-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2O2/c10-5-6-13-8-4-2-1-3-7(8)9(11)12/h1-4H,5-6,10H2,(H2,11,12)

58932-30-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-aminoethoxy)benzamide

1.2 Other means of identification

Product number -
Other names 2-(2-aminoethoxy)-benzamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:58932-30-2 SDS

58932-30-2Relevant articles and documents

Discovery of Novel pERK1/2- or β-Arrestin-Preferring 5-HT1AReceptor-Biased Agonists: Diversified Therapeutic-like versus Side Effect Profile

Sniecikowska, Joanna,Gluch-Lutwin, Monika,Bucki, Adam,Wi?ckowska, Anna,Siwek, Agata,Jastrzebska-Wiesek, Magdalena,Partyka, Anna,Wilczyńska, Daria,Pytka, Karolina,Latacz, Gniewomir,Przejczowska-Pomierny, Katarzyna,Wyska, El?bieta,Weso?owska, Anna,Paw?owski, Maciej,Newman-Tancredi, Adrian,Kolaczkowski, Marcin

supporting information, p. 10946 - 10971 (2020/11/09)

Novel 1-(1-benzoylpiperidin-4-yl)methanamine derivatives with high affinity and selectivity for serotonin 5-HT1A receptors were obtained and tested in four functional assays: ERK1/2 phosphorylation, adenylyl cyclase inhibition, calcium mobilization, and β-arrestin recruitment. Compounds 44 and 56 (2-methylaminophenoxyethyl and 2-(1H-indol-4-yloxy)ethyl derivatives, respectively) were selected as biased agonists with highly differential "signaling fingerprints"that translated into distinct in vivo profiles. In vitro, 44 showed biased agonism for ERK1/2 phosphorylation and, in vivo, it preferentially exerted an antidepressant-like effect in the Porsolt forced swimming test in rats. In contrast, compound 56 exhibited a first-in-class profile: it preferentially and potently activated β-arrestin recruitment in vitro and potently elicited lower lip retraction in vivo, a component of "serotonergic syndrome". Both compounds showed promising developability properties. The presented 5-HT1A receptor-biased agonists, preferentially targeting various signaling pathways, have the potential to become drug candidates for distinct central nervous system pathologies and possessing accentuated therapeutic activity and reduced side effects.

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