590418-04-5

Basic information

• Product Name: 3-Methyl-4-nitro-phenylboronic acid pinacol ester
• Synonyms: 3-Methyl-4-nitro-phenylboronic acid pinacol ester;2-Methyl-3-nitrobenzeneboronic acid pinacol ester;3-Methyl-4-nitro-phenylboronic acid picol ester
• CAS NO: 590418-04-5
• Molecular Formula: C₁₃H₁₈BNO₄
• Molecular Weight: 281
• Mol File: 590418-04-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Methyl-4-nitro-phenylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-4-nitro-phenylboronic acid pinacol ester(590418-04-5)
• EPA Substance Registry System: 3-Methyl-4-nitro-phenylboronic acid pinacol ester(590418-04-5)

Safety Data

• Hazardous Substances Data: 590418-04-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Methyl-4-nitro-phenylboronic acid pinacol ester is used as a reagent in organic synthesis for its ability to form stable complexes with a range of organic molecules. Its high stability and reactivity make it a popular choice for creating various organic molecules and pharmaceutical compounds.
Used in Cross-Coupling Reactions:
In the field of organic chemistry, 3-Methyl-4-nitro-phenylboronic acid pinacol ester is used as a reagent in cross-coupling reactions. Its high reactivity allows for the efficient formation of new chemical bonds, making it a crucial component in these reactions.
Used in Suzuki-Miyaura Reactions:
3-Methyl-4-nitro-phenylboronic acid pinacol ester is also used as a reagent in Suzuki-Miyaura reactions, a type of cross-coupling reaction used to form carbon-carbon bonds. Its stability and reactivity contribute to the successful formation of these bonds, making it an essential component in this reaction type.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Methyl-4-nitro-phenylboronic acid pinacol ester is used as a building block for the synthesis of various pharmaceutical compounds. Its ability to form stable complexes with organic molecules makes it a valuable tool in the development of new drugs and medicinal compounds.
Overall, 3-Methyl-4-nitro-phenylboronic acid pinacol ester is a versatile and crucial compound in the field of organic synthesis, with applications in various industries, including pharmaceuticals, due to its high stability, reactivity, and ability to form stable complexes with a wide range of organic molecules.

Downstream Products

• 1051930-31-4 tert-butyl 4-(3-methyl-4-nitrophenyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 590418-05-6 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES (PRMTS)

The present invention relates to compounds that are useful as inhibitors of protein arginine methyltransferase that have a formula selected from Formula (I), Formula (II) and Formula (III), as well as racemic mixtures, diastereomers, enantiomers and tautomers thereof and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof as defined herein. Said compound are useful as inhibitors of PRMTs and/or CARM-I. The invention further relates to compositions comprising such compounds and methods for their use.

Substituted phenylalkanoic acid derivatives and use thereof

A compound represented by the formula (I) or a salt thereof: wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R1(CH2)k— (wherein k represents 0 or an integer of 1 to 3; R1 represents a saturated cyclic alkyl group having 3 to 7 carbon atoms or a saturated condensed cyclic alkyl group having 6 to 8 carbon atoms, and the group R1 may be substituted with a lower alkyl group having 1 to 4 carbon atoms) and the like, and Ar represents a condensed bicyclic group such as naphthalen-1-yl group, which has suppressing action on prostaglandin and leukotriene production and is useful for prophylactic and/or therapeutic treatment of various inflammatory diseases and the like caused by these lipid mediators.