Combining chiral elements: A novel approach to asymmetric phase-transfer catalyst design
A new dicationic asymmetric phase-transfer catalyst, designed by combining chiral elements, is described. Catalytic testing using standard glycine imino ester alkylations shows good yields and moderate enantioselectivities.
Kowtoniuk, Walter E.,MacFarland, Darren K.,Grover, Gregory N.
p. 5703 - 5705
(2007/10/03)
Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides
This invention relates to a novel solution phase process for the preparation of amide, carbamate, and sulfonamide combinatorial libraries. These libraries have utility for drug discovery and are used to form wellplate components of novel assay kits.
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(2008/06/13)
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