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60016-62-8

CHEMBRDG-BB 6741358, also known as AZD0530, is a potent and selective inhibitor of the Src family of tyrosine kinases. It is a promising drug candidate with potential applications in cancer and other diseases.
Used in Oncology:
CHEMBRDG-BB 6741358 is used as an anti-cancer agent for its potential therapeutic use in treating various types of cancer, including breast cancer and prostate cancer. It exhibits promising anti-tumor activity by inhibiting the activity of Src, which plays a key role in cancer cell proliferation and metastasis.
Used in Inflammatory Disease Treatment:
CHEMBRDG-BB 6741358 is used as a potential treatment for inflammatory diseases due to its ability to target the Src family of tyrosine kinases, which are involved in inflammation processes.
Used in Osteoporosis Treatment:
CHEMBRDG-BB 6741358 is used as a potential treatment for osteoporosis, as it has been investigated for its possible use in managing bone loss and improving bone health.

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  • 60016-62-8 Structure

  • Basic information

    1. Product Name: CHEMBRDG-BB 6741358
    2. Synonyms: CHEMBRDG-BB 6741358;5-PROPYL-4H-1,2,4-TRIAZOL-3-AMINE;5-propyl-4H-1,2,4-triazol-3-amine(SALTDATA: FREE);3-Propyl-1H-1,2,4-triazol-5-amine
    3. CAS NO:60016-62-8
    4. Molecular Formula: C5H10N4
    5. Molecular Weight: 126.16
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 60016-62-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 331.2°C at 760 mmHg
    3. Flash Point: 180.5°C
    4. Appearance: /
    5. Density: 1.192g/cm3
    6. Vapor Pressure: 0.000158mmHg at 25°C
    7. Refractive Index: 1.581
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: CHEMBRDG-BB 6741358(CAS DataBase Reference)
    11. NIST Chemistry Reference: CHEMBRDG-BB 6741358(60016-62-8)
    12. EPA Substance Registry System: CHEMBRDG-BB 6741358(60016-62-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 60016-62-8(Hazardous Substances Data)

60016-62-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 60016-62-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,0,1 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 60016-62:
(7*6)+(6*0)+(5*0)+(4*1)+(3*6)+(2*6)+(1*2)=78
78 % 10 = 8
So 60016-62-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N4/c1-2-3-4-7-5(6)9-8-4/h2-3H2,1H3,(H3,6,7,8,9)

60016-62-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-propyl-1H-1,2,4-triazol-3-amine

1.2 Other means of identification

Product number -
Other names 3-Amino-5-n-propyl-1,2,4-triazol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60016-62-8 SDS

60016-62-8Downstream Products

60016-62-8Relevant articles and documents

Synthesis and evaluation of anti-HIV-1 and anti-HSV-1 activities of 4H-[1,2,4]-triazolo[1,5-a]pyrimidin-5-one derivatives

Abdel-Hafez, Atef A.,Elsherief, Hosny A. H.,Jo, Michiko,Kurokawa, Masahiko,Shiraki, Kimiyasu,Kawahata, Takuya,Otake, Toru,Nakamura, Norio,Hattori, Masao

, p. 833 - 839 (2007/10/03)

In a one pot procedure, 18 compounds of 7-(substituted phenyl)-2-substituted-6,7-dihydro-4H-[1,2,4] triazolo [1,5-a] pyrimidin-5-one derivatives (16-33) have been synthesized. 3(5)-Amino-5(3)-substituted-1,2,4-triazole derivatives (7-12) were used as synthones which were cyclocondensed by fusion with substituted methyl cinnamate esters (13-15) to afford the target compounds (16-33). In an effort to develop new non-nucleoside antiviral agents, compounds 16-33 were evaluated for their anti-HIV-1 and anti-HSV-1 activities. Complete inhibition of the proliferation of HIV-1 viruses was achieved by compounds 22, 23 and 24 at concentrations of 25, 25 and 50 μg/ml, respectively. 7-Phenyl-2-(n-pentyl)-6,7-dihydro-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one (19) exhibited potential activity against HSV-I with 88% reduction in the viral plaques. The suggested marked specificity of this class of compounds as anti-HIV-1 and HSV-1 agents is discussed.

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