607680-05-7Relevant articles and documents
On the bioactive conformation of the rhodopsin chromophore: Absolute sense of twist around the 6-s-cis bond
Fujimoto, Yukari,Ishihara, Jun,Maki, Shojiro,Fujioka, Naoko,Wang, Tao,Furuta, Takumi,Fishkin, Nathan,Borhan, Babak,Berova, Nina,Nakanishi, Koji
, p. 4198 - 4204 (2007/10/03)
Incubation of opsin with synthetic 6-s-locked retinoids 2a and 2b only led to pigment formation from the alpha-locked 2a, the CD spectrum of which was similar to that of native rhodopsin (Rh). This establishes that the 6-s-bond of the chromophore in rhodo