Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
Alkyne compounds having MCH-receptor antagonistic activity, which are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.
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Page/Page column 49-50
(2008/06/13)
NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS COMPRISING SAID COMPOUNDS
The invention relates to individual alkyne compounds with an antagonistic action against the MCH-receptor. Said compounds are suitable for producing medicaments for the treatment of metabolic disorders and/or eating disorders, in particular adiposity and diabetes.
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Page/Page column 111
(2008/06/13)
Synthesis and application to asymmetric allylic amination of substituted monodonor diazaphospholidine ligands
The synthesis of a series of substituted monodonor diazaphospholidine ligands is described. A regioselective lithiation process is a key step in one of these syntheses. The compounds are designed to be incorporated into soluble polymer and other solid pha
Edwards, Christopher W.,Shipton, Mark R.,Alcock, Nathaniel W.,Clase, Howard,Wills, Martin
p. 6473 - 6480
(2007/10/03)
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