61074-06-4

Basic information

• Product Name: guanosine dialdehyde
• Synonyms: guanosine dialdehyde
• CAS NO: 61074-06-4
• Molecular Formula: C10H11 N5 O5
• Molecular Weight: 281.22
• Mol File: 61074-06-4.mol

Chemical Properties

• Boiling Point: 618.2°C at 760 mmHg
• Flash Point: 327.7°C
• Appearance: /
• Density: 1.82g/cm³
• Vapor Pressure: 3.86E-16mmHg at 25°C
• Refractive Index: 1.76
• CAS DataBase Reference: guanosine dialdehyde(CAS DataBase Reference)
• NIST Chemistry Reference: guanosine dialdehyde(61074-06-4)
• EPA Substance Registry System: guanosine dialdehyde(61074-06-4)

Safety Data

• Hazardous Substances Data: 61074-06-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H11N5O5/c11-10-13-8-7(9(19)14-10)12-4-15(8)6(3-18)20-5(1-16)2-17/h1,3-6,17H,2H2,(H3,11,13,14,19)/t5-,6+/m0/s1

Upstream product

• 118-00-3 G 

Relevant articles and documents

Daunorubicin derivatives obtained from daunorubicin and nucleoside dialdehydes

Nucleoside dialdehydes were obtained by periodate oxidation of adenosine, cytidine, guanosine, uridine or 6-azauridine in the presence of Dowex (1x8; CH3COO-). Reductive alkylation of daunorubicin with these dialdehydes in the presence of NaBH3CN produced a series of 3'-deamino-3'- (4-morpholino)daunorubicin or 13-(R,S)-dihydrodaunorubicin derivatives, the latter being mixtures of two diastereomers at 13-C atom. The morpholino- daunorubicin derivatives containing nucleic base moieties are less cytotoxic than cyanomorpholino-daunorubicin, morpholino-daunorubicin and even than the parent antibiotic.