- Active-alkali metal-promoted reductive cleavage of chlorinated phenols
-
We investigated the degradation of chlorinated phenols under reductive electron transfer reaction conditions. Although Li and Na metal proved useless, activated forms of these metals, either their soluble naphthalene radical anions or 1,2-diarylethane dianions, promoted the degradation of the starting materials to various extents. Additionally, efficient dehalogenation of the sodium salts of several mono-, di-, and tri-chlorophenols was obtained by their reduction with an excess of Na metal and a catalytic amount of naphthalene. Springer-Verlag 2012.
- Azzena, Ugo,Dettori, Giovanna,Pisano, Luisa,Pittalis, Mario,Mangano, Giuseppe,Petretto, Giacomo,Pintore, Giorgio
-
experimental part
p. 601 - 605
(2012/07/28)
-
- [Pd(L)Cl2]-catalyzed selective hydroxylation of arylboronic acids to phenols
-
The palladium complex [Pd(L)Cl2] (1) has been prepared by the reaction of Pd(COD)Cl2 (COD = 1,5-cyclooctadiene) with L [N,N′-bis(diphenylphosphanyl)-2-(diphenylphosphanyl)ethanamine]. The ligand L and complex 1 have been characterized by elemental analysis, mass spectrometry and 1H/31P NMR spectroscopy. In the presence of O2, 1 selectively catalyzes the hydroxylation of a variety of arylboronic acids to the corresponding phenol derivatives in solvents with low-dielectric constants at 298 K, although in solvents with high dielectric constants the same reaction leads to the formation of both phenol and the coupled product, i.e. biaryl. The mechanistic aspects of the selective phenol formation from arylboronic acid with 1 have been addressed.
- Chowdhury, Abhishek Dutta,Mobin, Shaikh M.,Mukherjee, Soumen,Bhaduri, Sumit,Lahiri, Goutam Kumar
-
experimental part
p. 3232 - 3239
(2011/08/07)
-
- 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics
-
Analgesic 1,2,3,4-tetrahydroisoquinolines of the formula (1) STR1 wherein R1 and R2 respectively are hydrogen, hydroxy or alkoxy of 1 to 4 carbon atoms, R3 and R4 respectively are hydrogen or alkyl of 1 to 4 car
- -
-
-
- Anti-arteriosclerotic agents
-
Novel substituted arylene compounds and methods for their preparation and use are disclosed. These new compounds are useful as anti-arteriosclerotic agents.
- -
-
-
- Process for producing bisphenols
-
Bisphenols, substantially free of by-products, are produced rapidly by reacting a phenol and a compound of the formula STR1 wherein R and R' are independently selected from the group consisting of hydrogen, lower alkyl or aryl; X is lower acyloxy; Y is lower alkoxy, aryloxy or the same as X; Z is the divalent radical STR2 wherein R" and R'" are selected from the same category as R and R', and n is an integer from 3 to 9; m=(n-1).
- -
-
-