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CAS

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61318-91-0

Sulconazole nitrate is an antifungal agent that belongs to the imidazole class of drugs. It is a white to off-white crystalline powder with the chemical formula C18H14Cl2N2O and a molecular weight of 360.24 g/mol. Sulconazole nitrate works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, which leads to the disruption of the cell membrane's integrity and ultimately prevents fungal growth.

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  • 61318-91-0 Structure

  • Basic information

    1. Product Name: Sulconazole nitrate
    2. Synonyms: SULCONAZOLE NITRATE SALT;(+-)-1-(2,4-dichloro-beta-((4-chlorobenzyl)thio)phenethyl)imidazolenitrate;,mononitrate,(+-)-;1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazol;rs44872;1-[2-(P-CHLOROBENZYLTHIO)-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE NITRATE;1-[2-(P-CHLOROBENZYLTHIO)-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE NITRATE SALT;1-(2-[p-chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1h-imidazole
    3. CAS NO:61318-91-0
    4. Molecular Formula: C18H15Cl3N2S*HNO3
    5. Molecular Weight: 460.76
    6. EINECS: 1533716-785-6
    7. Product Categories: ZANTAC;Inhibitors
    8. Mol File: 61318-91-0.mol

  • Chemical Properties

    1. Melting Point: 130.5-132℃
    2. Boiling Point: 558.2 °C at 760 mmHg
    3. Flash Point: 291.4 °C
    4. Appearance: white/
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: room temp
    8. Solubility: N/A
    9. CAS DataBase Reference: Sulconazole nitrate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Sulconazole nitrate(61318-91-0)
    11. EPA Substance Registry System: Sulconazole nitrate(61318-91-0)

  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22
    3. Safety Statements: 36
    4. WGK Germany: 3
    5. RTECS: NI4475000
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 61318-91-0(Hazardous Substances Data)

61318-91-0 Usage

Uses

Used in Pharmaceutical Industry:
Sulconazole nitrate is used as a topical antifungal agent for the treatment of various fungal infections, such as athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It is effective against a wide range of dermatophytes, yeasts, and molds, making it a versatile treatment option for different types of fungal infections.
Used in Cosmetic Industry:
In the cosmetic industry, sulconazole nitrate is used as an active ingredient in antifungal creams, lotions, and shampoos. It helps in maintaining skin health by preventing and treating fungal infections that can cause skin irritation, itching, and discomfort.
Used in Veterinary Medicine:
Sulconazole nitrate is also used in veterinary medicine for the treatment of fungal infections in animals. It is particularly useful in treating infections caused by dermatophytes and yeasts, which can lead to skin and coat issues in pets.

Check Digit Verification of cas no

The CAS Registry Mumber 61318-91-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,1 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 61318-91:
(7*6)+(6*1)+(5*3)+(4*1)+(3*8)+(2*9)+(1*1)=110
110 % 10 = 0
So 61318-91-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

61318-91-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Sulconazole nitrate

1.2 Other means of identification

Product number -
Other names SULCONAZOLE NITRATE SALT

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61318-91-0 SDS

61318-91-0Downstream Products

61318-91-0Relevant articles and documents

Methods and compositions for intravaginal contraception

-

, (2008/06/13)

A gel formulation, which is inherently spermicidal and which provides an efficient delivery system for spermicidal and other contraceptively effective compounds intravaginally is disclosed. Said formulation is useful in methods of intravaginal contraception.

1-[β(R-thio)phenethyl]imidazoles and derivatives thereof

-

, (2008/06/13)

Novel 1-[β-(R-thio)phenethyl]-imidazoles and the corresponding 1-[β-(R-sulfinyl)phenethyl]imidazoles and 1-[β-(R-sulfonyl)phenethyl]imidazoles wherein R is alkyl, alkenyl, aralkenyl, substituted aralkenyl, alkynyl, cycloalkyl, cycloalkyl alkyl, aralkyl, substituted aralkyl, aryl or substituted aryl; and the antimicrobial acid addition salts thereof, are useful as antifungal, anti-bacterial and anti-protozoal agents.

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