61755-97-3

Basic information

• Product Name: 5-HYDROXYCYCLOOCTANONE
• Synonyms: 5-HYDROXYCYCLOOCTANONE
• CAS NO: 61755-97-3
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.2
• Mol File: 61755-97-3.mol

Chemical Properties

• Melting Point: 99-100 °C
• Boiling Point: 261.8 °C at 760 mmHg
• Flash Point: 108.6 °C
• Appearance: /
• Density: 1.05 g/cm³
• Vapor Pressure: 0.00162mmHg at 25°C
• Refractive Index: 1.482
• PKA: 14.98±0.20(Predicted)
• CAS DataBase Reference: 5-HYDROXYCYCLOOCTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-HYDROXYCYCLOOCTANONE(61755-97-3)
• EPA Substance Registry System: 5-HYDROXYCYCLOOCTANONE(61755-97-3)

Safety Data

• Hazardous Substances Data: 61755-97-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Hydroxycyclooctanone is used as an intermediate in the synthesis of pharmaceutical compounds for its ability to facilitate the creation of complex organic molecules that can target specific biological pathways.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Hydroxycyclooctanone serves as a key intermediate, contributing to the development of new pesticides or other agricultural chemicals that can enhance crop protection and yield.
Used in Material Science:
5-Hydroxycyclooctanone is utilized in material science applications, where it can be incorporated into the development of advanced materials with specific properties, such as improved strength, flexibility, or chemical resistance.
Overall, 5-Hydroxycyclooctanone's versatility and potential applications across various industries underscore its importance as a fundamental component in the synthesis of a wide range of organic compounds.

InChI:InChI=1/C8H14O2/c9-7-3-1-4-8(10)6-2-5-7/h7,9H,1-6H2

Upstream product

• 55343-44-7 cyclooctane-1,5-diol 

Downstream Products

• 55343-44-7 cyclooctane-1,5-diol 
• 4277-34-3 (Z)-cyclooct-4-enol 
• 74671-05-9 4-Cyclooctin-1-yl-(4-nitrobenzoat) 
• 23435-05-4 5-Benzyloxy-cyclooctanol-⁽¹⁾ 
• 152941-19-0 5-Benzyloxy-cyclooctanon-⁽¹⁾ 

Relevant articles and documents

One-pot regio- and stereoselective cyclization of 1,2,n-triols

A simple and efficient process to cyclize triols containing a 1,2-diol functionality with a pendant hydroxyl group is presented. The one-pot procedure converts the 1,2-diol into an ortho ester in situ, which upon treatment with a Lewis acid generates a cyclic acetoxonium intermediate. This intermediate is subsequently trapped by the pendant hydroxyl group to generate a cyclic ether. The stereochemistry of the 1,2-diol is transferred to the product with complete fidelity (inversion at the site of cyclization), and the reaction proceeds with high regioselectivity. The process is akin to the Lewis acid-catalyzed intramolecular ring-opening of epoxides with hydroxyl groups yielding cyclic ethers of various sizes with regio- and stereochemical control. Copyright

PYRROLIDINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME

The present invention provides a compound which has cytokine production inhibitory activity and is useful for the treatment of diseases which is associated with cytokine. The compound is represented by the following general formula (I) [wherein A represents a cyclic group which may be substituted; the partial structure -D---E- represents a group represented by -CH2CH2- or -CH=CH-; W reprensents a group represented by -CH2-, - CHzCH2-, -CH=CH- or -CH=; the partial structure >X---Y- represents a group represented by >CH-(CH2)n-, >C=CH-, >CH-CH2-CH(OH)-, >CH-CH2-C (=O) -, >CH-O- or >CH-O-CO-, provided that when W is -CH=, then X---Y- represents C-(CH2)p-; Z represents a divalent aliphatic hydrocarbon group; R1 and R2, which may be the same or different, each represents a hydrogen atom, or a hydroxyl, alkoxy or alkoxyalkoxy group; m is an integer of 0 or 1] .