617688-39-8

Basic information

• Product Name: 2-AMINO-4,5-DIHYDRONAPHTHO[1,2-B]THIOPHENE-3-CARBOXAMIDE
• Synonyms: 2-AMINO-4,5-DIHYDRONAPHTHO[1,2-B]THIOPHENE-3-CARBOXAMIDE;2-amino-4,5-dihydrobenzo[g][1]benzothiole-3-carboxamide;2-amino-4,5-dihydrobenzo[g]benzothiophene-3-carboxamide
• CAS NO: 617688-39-8
• Molecular Formula: C13H12N2OS
• Molecular Weight: 244.31218
• Mol File: 617688-39-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-4,5-DIHYDRONAPHTHO[1,2-B]THIOPHENE-3-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4,5-DIHYDRONAPHTHO[1,2-B]THIOPHENE-3-CARBOXAMIDE(617688-39-8)
• EPA Substance Registry System: 2-AMINO-4,5-DIHYDRONAPHTHO[1,2-B]THIOPHENE-3-CARBOXAMIDE(617688-39-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 617688-39-8(Hazardous Substances Data)

Usage

Class

Carboxamide

Structure

Heteroaromatic compound with a naphtho[1,2-b]thiophene core and an amino group at the 2-position

Potential Applications

Medicinal chemistry, drug development

Biological Activities

Potential pharmacological properties

Building Block

Used in the synthesis of new drug candidates

Additional Research

Necessary to fully understand properties and potential applications

Upstream product

• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 107-91-5 cyanoacetic acid amide 

Relevant articles and documents

SUBSTITUTED THIOPHENE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION

The present invention provides substituted thiophene carboxamide compounds having structural Formula I and isomers, tautomers, polymorphs, carriers, prodrugs, and pharmaceutically acceptable salts thereof, compositions comprising such, and methods for treating diseases associated with kinase activity. More specifically, the present invention provides methods of treatment of a variety of diseases associated with IKK2 including the treatment of inflammation, other inflammation-associated disorders, such as, as an analgesic in the treatment of pain and headaches, arthritis, including but not limited to rheumatoid arthritis, asthma, gastrointestinal conditions such as inflammatory bowel disease, vascular diseases, viral infections such as AIDS, and cancer.