618069-78-6

Basic information

• Product Name: N-(2,6-diisopropylphenyl)-1-naphthamide
• Synonyms: N-(2,6-diisopropylphenyl)-1-naphthamide
• CAS NO: 618069-78-6
• Molecular Formula: C₂₃H₂₅NO
• Molecular Weight: 331.457
• Mol File: 618069-78-6.mol

Chemical Properties

• Boiling Point: 405.7±34.0 °C(Predicted)
• Appearance: /
• Density: 1.095±0.06 g/cm3(Predicted)
• PKA: 13.20±0.70(Predicted)
• CAS DataBase Reference: N-(2,6-diisopropylphenyl)-1-naphthamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-diisopropylphenyl)-1-naphthamide(618069-78-6)
• EPA Substance Registry System: N-(2,6-diisopropylphenyl)-1-naphthamide(618069-78-6)

Safety Data

• Hazardous Substances Data: 618069-78-6(Hazardous Substances Data)

Upstream product

• 24544-04-5 2,6-diisopropylbenzenamine 
• 879-18-5 naphthalene-1-carbonic acid chloride 
• 90-14-2 1-Iodonaphthalene 
• 201230-82-2 carbon monoxide 

Downstream Products

• 213182-97-9 2,6-iPr₂C₆H₃N=C(C₁₀H₈)(Cl) 
• 1173901-03-5 bis(N-2',6'-diisopropylphenyl(naphthyl)amidate)mono(trimethylsilylamido)yttrium mono(tetrahyrofuran) 
• 1058207-13-8 Y((C₁₀H₇)CON(C₆H₃(CH(CH₃)2)2))2((C₁₀H₇)CON(C₆H₃(CH(CH₃)2)2))((C₁₀H₇)CONH(C₆H₃(CH(CH₃)2)2)) 
• 1058207-03-6 tris(N-2',6'-diisopropylphenyl(naphthyl)amidate)yttrium mono(tetrahydrofurane) 

Relevant articles and documents

Functional Group Transposition: A Palladium-Catalyzed Metathesis of Ar-X σ-Bonds and Acid Chloride Synthesis

We describe the development of a new method to use palladium catalysis to form functionalized aromatics: via the metathesis of covalent σ-bonds between Ar-X fragments. This transformation demonstrates the dynamic nature of palladium-based oxidative addition/reductive elimination and offers a straightforward approach to incorporate reactive functional groups into aryl halides through exchange reactions. The reaction has been exploited to assemble acid chlorides without the use of high energy halogenating or toxic reagents and, instead, via the metathesis of aryl iodides with other acid chlorides.

Highly efficient aminocarbonylation of iodoarenes at atmospheric pressure catalyzed by a robust acenaphthoimidazolyidene allylic palladium complex

A robust allylic palladium-NHC complex was developed and exhibited extremely high catalytic activity toward aminocarbonylation of various (hetero)aryl iodides under atmospheric carbon monoxide pressure, in which a broad range of secondary and primary amines were well tolerated. In addition, the concise synthesis of an anticancer drug tamibarotene was accomplished even in a gram scale, further highlighting the practical applicability of the protocol.