- Asymmetric Construction of Highly Functionalized Spirobarbiturate-Cyclopentenes through Chiral Phosphine-Catalyzed [3+2] Annulation of Morita–Baylis–Hillman Carbonates with Barbiturate-Derived Alkenes
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A multifunctional chiral phosphine-catalyzed enantioselective [3+2] annulation of Morita–Baylis–Hillman carbonates with barbiturate-derived alkenes has been achieved under mild conditions, providing a variety of chiral spirobarbiturate-cyclopentenes in moderate to excellent yields with moderate to excellent diastereo- and enantioselectivities. (Figure presented.).
- Liu, Yang,Yang, Wenjun,Wu, Yang,Mao, Biming,Gao, Xing,Liu, Honglei,Sun, Zhanhu,Xiao, Yumei,Guo, Hongchao
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supporting information
p. 2867 - 2872
(2016/09/16)
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- Synthesis of spiro 3-bromo-4,5-dihydroisoxazoles via [1,3]dipolar cycloaddition reactions
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A group of novel 4-bromo-7,9-dimethyl-1-aryl-2-oxa-3,7,9-triaza-spiro[4.5]dec-3-ene-6,8,10-trione derivatives is prepared through 1,3-dipolar cycloadditions between benzylidenes and bromonitrile oxide. This reaction is shown to have high atom economy.
- Soleimani, Ebrahim,Yazdani, Hossein,Saei, Parisa
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supporting information
p. 1635 - 1637
(2015/03/14)
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- A novel, one-pot, efficient synthesis of 2-aroyl-1,4-diaryl-7,9-dimethyl-7, 9-diazaspiro[4.5]deca-1,3-diene-6,8,10-triones
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A novel and efficient synthesis of 2-aroyl-1,4-diaryl-7,9-dimethyl-7,9- diazaspiro[4.5]deca-1,3-diene-6,8,10-triones is described. The reactive 1:1 zwitterionic intermediate, formed by the addition of triphenylphosphine to diaroylacetylenes, was trapped by a Knoevenagel condensation product prepared in situ by reaction of AyV-dimethylbarbituric acid and aromatic aldehydes, to afford the title compounds in excellent yields under mild reaction conditions.
- Adib, Mehdi,Sayahi, Mohammad Hosein,Ziyadi, Hakimeh,Zhu, Long-Guan,Bijanzadeh, Hamid Reza
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experimental part
p. 3289 - 3294
(2009/05/11)
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