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62036-49-1

CHEMBRDG-BB 6141880 is a pyrazinopyridine derivative with the molecular formula C20H19N3O4. It is a potent and selective inhibitor of the poly (ADP-ribose) polymerase (PARP) enzyme, which is crucial for DNA repair and maintaining genomic stability. The inhibition of PARP is associated with the treatment of various cancers, especially those with deficiencies in DNA repair pathways. CHEMBRDG-BB 6141880 has demonstrated promising activity in preclinical studies and is being explored as a potential therapeutic agent for cancer treatment. However, further research is necessary to assess its safety and efficacy in clinical settings.

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  • 62036-49-1 Structure

  • Basic information

    1. Product Name: CHEMBRDG-BB 6141880
    2. Synonyms: CHEMBRDG-BB 6141880;4-ETHYL-5-HYDROXY-7-METHYL-2H-CHROMEN-2-ONE;OTAVA-BB 1090193;4-ethyl-5-hydroxy-7-methyl-2H-chromen-2-one(SALTDATA: FREE);4-ethyl-5-hydroxy-7-methyl-2-chromenone;4-ethyl-5-hydroxy-7-methyl-chromen-2-one;4-ethyl-5-hydroxy-7-methylchromen-2-one;4-ethyl-5-hydroxy-7-methyl-coumarin
    3. CAS NO:62036-49-1
    4. Molecular Formula: C12H12O3
    5. Molecular Weight: 204.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 62036-49-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 380.4°C at 760 mmHg
    3. Flash Point: 168.2°C
    4. Appearance: /
    5. Density: 1.22g/cm3
    6. Vapor Pressure: 2.5E-06mmHg at 25°C
    7. Refractive Index: 1.581
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: CHEMBRDG-BB 6141880(CAS DataBase Reference)
    11. NIST Chemistry Reference: CHEMBRDG-BB 6141880(62036-49-1)
    12. EPA Substance Registry System: CHEMBRDG-BB 6141880(62036-49-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 62036-49-1(Hazardous Substances Data)

62036-49-1 Usage

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 6141880 is used as a therapeutic agent for the treatment of various cancers. Its application is based on its ability to inhibit the PARP enzyme, which is involved in DNA repair and genomic stability maintenance. This inhibition is particularly beneficial for cancers with deficiencies in DNA repair pathways, making CHEMBRDG-BB 6141880 a promising candidate for cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 62036-49-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,0,3 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 62036-49:
(7*6)+(6*2)+(5*0)+(4*3)+(3*6)+(2*4)+(1*9)=101
101 % 10 = 1
So 62036-49-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H12O3/c1-3-8-6-11(14)15-10-5-7(2)4-9(13)12(8)10/h4-6,13H,3H2,1-2H3

62036-49-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-ethyl-5-hydroxy-7-methylchromen-2-one

1.2 Other means of identification

Product number -
Other names HMS2266I03

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:62036-49-1 SDS

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