Synthesis and Preliminary Biological Evaluations of Ionic and Nonionic Amphiphilic α-Phenyl-N-tert-butylnitrone Derivatives
In this study we report the synthesis of a series of new amphiphilic compounds derived from α-phenyl-N-tert-butylnitrone (PBN). The nitrone function was fitted into the core of the molecule between its polar and apolar goups. The polar head consisted of a
Durand, Grégory,Polidori, Ange,Ouari, Olivier,Tordo, Paul,Geromel, Vanna,Rustin, Pierre,Pucci, Bernard
p. 5230 - 5237
(2007/10/03)
Synthesis of a new family of glycolipidic nitrones as potential antioxidant drugs for neurodegenerative disorders
This paper deals with the synthesis of a novel series of amphiphilic glycosylated spin-traps derived from α-Phenyl-N-tert-butyl nitrone (PBN) and an initial characterization of their anti-caspase-3 activity. Preliminary investigation of their anti-apoptos
Durand, Gregory,Polidori, Ange,Salles, Jean-Pierre,Pucci, Bernard
p. 859 - 862
(2007/10/03)
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