623565-69-5

Basic information

• Product Name: (4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL
• Synonyms: (4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL;Pyrazolo[1,5-a]pyrazine-2-methanol, 4,5,6,7-tetrahydro-;{4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-yl}methanol
• CAS NO: 623565-69-5
• Molecular Formula: C7H11N3O
• Molecular Weight: 153.18
• Mol File: 623565-69-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL(623565-69-5)
• EPA Substance Registry System: (4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL(623565-69-5)

Safety Data

• Hazardous Substances Data: 623565-69-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
(4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL is used as a building block for the synthesis of more complex organic molecules, leveraging its unique ring structure and functional groups to create a diverse array of chemical entities.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL is utilized as a key intermediate in the development of new pharmaceuticals, potentially contributing to the creation of drugs with novel mechanisms of action and therapeutic profiles.
Used in Pharmaceutical Development:
(4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL is employed as a starting material for the design and synthesis of innovative drug candidates, with the aim of discovering compounds with enhanced efficacy, selectivity, and safety profiles for the treatment of various diseases and conditions.
Used in Chemical Process Research:
(4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZIN-2-YL)METHANOL is also used as a subject of study in chemical process research to understand its reactivity, stability, and potential applications in catalytic systems or as part of green chemistry initiatives, focusing on the development of more sustainable and efficient chemical synthesis methods.

Upstream product

• 951626-95-2 ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate 
• 1380507-24-3 diethyl 1-{2-[(tert-butoxycarbonyl)amino]ethyl}-1H-pyrazole-3,5-dicarboxylate 
• 623565-16-2 2-hydroxymethyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carboxylic acid 4-nitrobenzyl ester 

Relevant articles and documents

MACROCYCLIC COMPOUNDS

Disclosed are macrocyclic compounds of formula (I) comprising a 2-carboxy indole ring. Such compounds, and their pharmaceutically acceptable salts, are useful as Mcl-1 (myeloid cell leukemia-1) inhibitors. The compounds may be used in treating a disease o

Bicyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors

This invention relates to certain bicyclic 6-alkylidene penems which act as a inhibitor of class-D enzymes. β-Lactamases hydrolyze β-lactam antibiotics, and as such serve as the primary cause of bacterial resistance. The compounds of the present invention when combined with β-lactam antibiotics will provide an effective treatment against life threatening bacterial infections. In accordance with the present invention there are provided compounds of general formula I or a pharmaceutically acceptable salt or in vivo hydrolyzable ester R5 thereof: wherein: One of A and B denotes hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X═O or S.

BICYCLIC 6-ALKYLIDENE-PENEMS AS ?-LACTAMASES INHIBITORS

The present invention provides a compound of Formula (I), pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.