62438-03-3

Basic information

• Product Name: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE
• Synonyms: CHEMBRDG-BB 3007474;ART-CHEM-BB B007474;5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE;5-METHYLISOXAZOLE-3-CARBOHYDRAZIDE;AKOS B007474;SALOR-INT L482595-1EA;5-Methylisoxazole-3-carboxylicacidhydrazide,99%;3-Isoxazolecarboxylicacid,5-methyl-,hydrazide(7CI,9CI)
• CAS NO: 62438-03-3
• Molecular Formula: C₅H₇N₃O₂
• Molecular Weight: 141.13
• Product Categories: AMIDE;Heterocycles;Intermediates
• Mol File: 62438-03-3.mol

Chemical Properties

• Appearance: /
• Density: 1.291 g/cm³
• Refractive Index: 1.534
• Storage Temp.: 2-8°C
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE(62438-03-3)
• EPA Substance Registry System: 5-METHYL-ISOXAZOLE-3-CARBOXYLIC ACID HYDRAZIDE(62438-03-3)

Safety Data

• Hazard Codes: Xi
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37:Wear suitable p
• HazardClass: IRRITANT
• Hazardous Substances Data: 62438-03-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H7N3O2/c1-3-2-4(8-10-3)5(9)7-6/h2H,6H2,1H3,(H,7,9)

Upstream product

• 19788-35-3 methyl 5-methylisoxazole-3-carboxylate 
• 3209-72-1 ethyl 5-methylisoxazole-3-carboxylate 

Downstream Products

• 93569-42-7 5-methyl-isoxazole-3-carboxylic acid (3-dimethylamino-benzylidene)-hydrazide 
• 99673-55-9 1-biphenyl-4-yl-pentane-1,4-dione bis-[(5-methyl-isoxazole-3-carbonyl)-hydrazone] 
• 92296-35-0 5-methyl-isoxazole-3-carboxylic acid (2-dimethylamino-benzylidene)-hydrazide 
• 96730-89-1 5-methyl-isoxazole-3-carboxylic acid phenethylidenehydrazide 
• 100123-75-9 5-methyl-isoxazole-3-carboxylic acid (2-chloro-benzylidene)-hydrazide 
• 91397-11-4 5-methyl-isoxazole-3-carboxylic acid benzylidenehydrazide 
• 99989-35-2 5-methyl-isoxazole-3-carboxylic acid (2-hydroxy-benzylidene)-hydrazide 
• 90000-70-7 Aethyliden-<5-Methyl-3-isoxazolylcarbonyl>-hydrazin 
• 93538-85-3 5-methyl-isoxazole-3-carboxylic acid (4-diethylamino-benzylidene)-hydrazide 
• 92296-36-1 5-methyl-isoxazole-3-carboxylic acid (4-dimethylamino-benzylidene)-hydrazide 
• 92290-48-7 5-methyl-isoxazole-3-carboxylic acid N'-benzenesulfonyl-hydrazide 
• 92547-98-3 5-methyl-isoxazole-3-carboxylic acid (4-isopropyl-benzylidene)-hydrazide 
• 69352-52-9 1-Benzyl-1-<5-methyl-3-isoxazolyl-carbonyl)-hydrazin 
• 69352-53-0 1-<4-Dimethylamino-benzyl>-1-<5-methyl-isoxazolyl-(3)-carbonyl>-hydrazin 

Relevant articles and documents

Pyridine methylamino dithio formic acid heteroaryl naphthenic base ester compound and preparation method and application thereof

The invention relates to a compound as shown in a general formula (I) or pharmaceutically acceptable salts or solvates thereof, and relates to a preparation method of the compound and application thereof in preparing anti-tumor drugs. Please see the general formula (I) in the description.

TUBULIN INHIBITORS

The present invention relates to a compound of Formula (I) for use as a medicament, wherein: m is 0, 1, 2, 3, 4, or 5; R1 and R2 together form a five-membered, six-membered, or seven-membered ring, wherein R1 and R2 together as a group is -(CH2)3-, -(CH2)4 -, or -(CH2)5-; R3 at each occurrence is independently selected from the group consisting of H, halogen, hydroxyl, alkoxy, and a substituted or unsubstituted C1-C5 alkyl; and R4 is H, halogen, or a substituted or unsubstituted C1-C5 alkyl

Compounds Which Selectively Modulate The CB2 Receptor

Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

TRIAZOLO-PYRIDAZINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF NEUROPATHIC PAIN

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Pentaaza-cyclopental[a]naphthalene derivatives as ligands for GABAa α5 receptors

A class of 1,2,3a,4,x-pentaaza-cyclopenta[a]naphthalene compounds (x=6, 7, 8 or 9) is described. The compounds have a high affinity for the GABAAα5 receptors and show inverse agonist activity thereat. The compounds are useful in therapy where cognition enhancement is required.