Welcome to LookChem.com Sign In|Join Free

CAS

  • or

625370-80-1

4-(TRIFLUOROMETHYL)-6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBONITRILE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

625370-80-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

  • 4-(Trifluoromethyl)-6-(4-fluorophenyl)-1,2-dihydro-2-thioxopyridine-3-carbonitrile

    Cas No: 625370-80-1

  • USD $ 1.9-2.9 / Gram

  • 100 Gram

  • 1000 Metric Ton/Month

  • Chemlyte Solutions
  • Contact Supplier

  • 4-(TRIFLUOROMETHYL)-6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBONITRILE

    Cas No: 625370-80-1

  • No Data

  • No Data

  • No Data

  • HETEROCYCLICS
  • Contact Supplier
  • 625370-80-1 Structure

  • Basic information

    1. Product Name: 4-(TRIFLUOROMETHYL)-6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBONITRILE
    2. Synonyms: 4-(TRIFLUOROMETHYL)-6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBONITRILE;6-(4-FLUOROPHENYL)-2-THIOXO-4-(TRIFLUOROMETHYL)-1,2-DIHYDRO-3-PYRIDINECARBONITRILE;AKOS USSH-4110021
    3. CAS NO:625370-80-1
    4. Molecular Formula: C13H6F4N2S
    5. Molecular Weight: 298.26
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 625370-80-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(TRIFLUOROMETHYL)-6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBONITRILE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(TRIFLUOROMETHYL)-6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBONITRILE(625370-80-1)
    11. EPA Substance Registry System: 4-(TRIFLUOROMETHYL)-6-(4-FLUOROPHENYL)-1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBONITRILE(625370-80-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 625370-80-1(Hazardous Substances Data)

625370-80-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 625370-80-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,5,3,7 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 625370-80:
(8*6)+(7*2)+(6*5)+(5*3)+(4*7)+(3*0)+(2*8)+(1*0)=151
151 % 10 = 1
So 625370-80-1 is a valid CAS Registry Number.

625370-80-1Downstream Products

625370-80-1Relevant articles and documents

Discovery and structure-activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors

Wang, Ning-Yu,Zuo, Wei-Qiong,Xu, Ying,Gao, Chao,Zeng, Xiu-Xiu,Zhang, Li-Dan,You, Xin-Yu,Peng, Cui-Ting,Shen, Yang,Yang, Sheng-Yong,Wei, Yu-Quan,Yu, Luo-Ting

, p. 1581 - 1588 (2014/03/21)

Current treatment for hepatitis C is barely satisfactory, there is an urgent need to develop novel agents for combating hepatitis C virus infection. This study discovered a new class of thieno[2,3-b]pyridine derivatives as HCV inhibitors. First, a hit compound characterized by a thienopyridine core was identified in a cell-based screening of our privileged small molecule library. And then, structure activity relationship study of the hit compound led to the discovery of several potent compounds without obvious cytotoxicity in vitro (12c, EC50 = 3.3 μM, SI >30.3, 12b, EC50 = 3.5 μM, SI >28.6, 10l, EC50 = 3.9 μM, SI >25.6, 12o, EC 50 = 4.5 μM, SI >22.2, respectively). Although the mechanism of them had not been clearly elucidated, our preliminary optimization of this class of compounds had provided us a start point to develop new anti-HCV agents.

3-Amino-6-aryl(or 6-heteroaryl)-4-R2-thieno[2,3-b]pyridin-2-carboxylic acid amides, pharmaceutical compositions comprising the said and their use as inhibitors of TNFalpha release

-

Page/Page column 19, (2008/06/13)

3-Amino-6-(hetero)aryl-thieno[2,3-b]pyridin-2-carboxylic acid amide derivatives (I) and their solvates, salts, prodrugs formulations, active metabolites or optionally tautomers are new. 3-Amino-6-(hetero)aryl-thieno[2,3-b]pyridin-2-carboxylic acid amide d

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 625370-80-1