A Novel Preparation of 5,6,7,8-Tetrahydroquinazolin-4(3H)-ones
Cyclocondensation of 2-oxocyclohexanecarboxamide with aldehydes and ammonia affords 4-oxo-1,2,5,6,7,8-hexahydroquinazolines which are conveniently dehydrogenated to the title compounds by treatment with palladium-on-carbon catalyst in boiling toluene.
Fueloep, Ferenc,Bernath, Gabor
p. 1148 - 1149
(2007/10/02)
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