- Pyrazolo-cyclic compound, pharmaceutical composition containing pyrazolo-cyclic compound, and preparation method and application of pyrazolo-cyclic compound
-
The invention belongs to the field of medicinal chemistry, and relates to a pyrazolo-cyclic compound, a pharmaceutical composition containing the pyrazolo-cyclic compound, and a preparation method and application of the pyrazolo-cyclic compound. Specifica
- -
-
Paragraph 0443-0444; 0448-0450
(2021/04/26)
-
- Nickel-catalyzed amination of aryl fluorides with primary amines
-
The Ni-catalyzed cross-coupling reaction between aryl fluorides and primary amines was enabled by the 1,2-bis(dicyclohexylphosphino)benzene (DCYPBz) or 1,2-bis(dicyclohexylphosphino)ethane (DCYPE) ligands. Both N-alkyl- and N-aryl-substituted primary amin
- Harada, Tomoya,Ueda, Yusuke,Iwai, Tomohiro,Sawamura, Masaya
-
supporting information
p. 1718 - 1721
(2018/02/21)
-
- Desymmetrization of cyclohexadienones viad-camphor-derived triazolium salt catalyzed intramolecular Stetter reaction
-
Enantioselective desymmetrization of cyclohexadienones via a d-camphor-derived triazolium salt catalyzed intramolecular Stetter reaction was realized. With 10 mol% of camphor-derived triazolium salt E and 10 mol% of DIEA, various substituted cyclohexadienones proceeded through an intramolecular Stetter reaction, affording tricyclic products in moderate to good yields and excellent ee.
- Jia, Min-Qiang,You, Shu-Li
-
supporting information; experimental part
p. 6363 - 6365
(2012/08/14)
-
- Cathepsin K inhibitors
-
The present invention provides a compound of the Formula: a pharmaceutically acceptable salt, a solvate, or a prodrug thereof, wherein m, n, Ar1, R1, R2, R3, R4, and R5 are those defined he
- -
-
Page/Page column 46
(2010/11/25)
-