626220-65-3

Basic information

• Product Name: 2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
• Synonyms: 2-(BOC-AMINOMETHYL)-3-(4-CHLORO-PHENYL)-PROPIONIC ACID;Benzenepropanoic acid, 4-chloro-.alpha.-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-;3-(Boc-amino)-2-(4-chlorobenzyl)propanoic acid
• CAS NO: 626220-65-3
• Molecular Formula: C₁₅H₂₀ClNO₄
• Molecular Weight: 313.779
• Mol File: 626220-65-3.mol

Chemical Properties

• Boiling Point: 466.5°C at 760 mmHg
• Flash Point: 235.9°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 1.68E-09mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: 2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID(626220-65-3)
• EPA Substance Registry System: 2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID(626220-65-3)

Safety Data

• Hazardous Substances Data: 626220-65-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID is used as a reagent in pharmaceutical research for its broad applicability in chemical reactions. It is particularly useful in the synthesis of various medicines, especially those targeting psychological disorders.
Used in Peptide Synthesis:
In the field of peptide synthesis, 2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID is used as a BOC Amino Acid, which is characterized by a BOC protective group. This protective group is essential in preventing unwanted side reactions during the synthesis process, allowing for the efficient production of desired peptide sequences.
Used in Chemical Reactions:
2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID is used in various chemical reactions due to its complex structure and the presence of multiple elements such as chlorine, carbon, hydrogen, nitrogen, and oxygen. Its versatility makes it a valuable compound in the development of new chemical processes and products.
Used in Chemical and Pharmaceutical Industries:
In the chemical and pharmaceutical industries, 2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID is used as a key component in the production of various medicines and pharmaceutical products. Its involvement in reactions leading to the synthesis of these medicines highlights its importance in the development of new treatments for psychological disorders and other health conditions.

InChI:InChI=1/C15H20ClNO4/c1-15(2,3)21-14(20)17-9-11(13(18)19)8-10-4-6-12(16)7-5-10/h4-7,11H,8-9H2,1-3H3,(H,17,20)(H,18,19)

Upstream product

• 886366-43-4 methyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzyl)propanoate 

Downstream Products

• 1172068-25-5 tert-butyl 2-(4-chlorobenzyl)-3-(4-(3-methyl-5-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazin-1-yl)-3-oxopropylcarbamate 

Relevant articles and documents

PYRROLOPYRIDINES AS KINASE INHIBITORS

Compounds of Formula (I) are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.Formula, (I).

PYRAZOLOPYRIDINES AS KINASE INHIBITORS

Compounds of Formula I are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.