628284-75-3

Basic information

• Product Name: 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE
• Synonyms: 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE ;6-Fluoro-3-nitro-quinolin-4-ol;4-Quinolinol, 6-fluoro-3-nitro-
• CAS NO: 628284-75-3
• Molecular Formula: C9H5FN2O3
• Molecular Weight: 208.1460032
• Mol File: 628284-75-3.mol

Chemical Properties

• Boiling Point: 338.2°C at 760 mmHg
• Flash Point: 158.4°C
• Appearance: /
• Density: 1.585g/cm³
• Vapor Pressure: 5.08E-05mmHg at 25°C
• Refractive Index: 1.697
• CAS DataBase Reference: 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE(628284-75-3)
• EPA Substance Registry System: 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE(628284-75-3)

Safety Data

• Hazardous Substances Data: 628284-75-3(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
6-FLUORO-4-HYDROXY-3-NITROQUINOLINE is used as a pharmaceutical candidate for its anti-microbial, anti-cancer, and anti-inflammatory properties. Its unique structure allows it to interact with various biological targets, making it a promising agent for the development of new drugs to treat a range of diseases.
Used in Drug Development:
In the pharmaceutical industry, 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE is utilized as a lead compound in the discovery and optimization of novel therapeutic agents. Its diverse biological activities and chemical properties facilitate the design of drugs with improved efficacy, selectivity, and safety profiles.
Used in Research:
6-FLUORO-4-HYDROXY-3-NITROQUINOLINE serves as a valuable research tool in the study of biological pathways and mechanisms. Its ability to modulate various cellular processes makes it useful for investigating the roles of specific proteins, enzymes, and signaling pathways in health and disease.
Used in Organic Synthesis:
As a building block in the synthesis of complex organic molecules, 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE is employed in the chemical industry for the creation of advanced materials, pharmaceuticals, and other specialty chemicals. Its unique structural features and reactivity contribute to the development of innovative synthetic strategies and products.
Further research and testing are necessary to fully explore the potential uses and effects of 6-FLUORO-4-HYDROXY-3-NITROQUINOLINE, ensuring its safe and effective application in various industries.

InChI:InChI=1/C9H5FN2O3/c10-5-1-2-7-6(3-5)9(13)8(4-11-7)12(14)15/h1-4H,(H,11,13)

Downstream Products

• 99010-07-8 4-chloro-6-fluoro-3-nitroquinoline 

Relevant articles and documents

CYCLIC SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE DERIVATIVES

The present invention provides novel cyclic substituted imidazo[4,5- c]quinoline derivatives of Formula (I), and the pharmaceutically acceptable salts thereof, wherein R1, R2, R4, R5, R6, X and Z are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising the compounds of Formula I and to use of the compounds in the treatment of diseases associated with LRRK2, such as neurodegenerative diseases including Parkinson's disease or Alzheimer's disease, cancer, Crohn's disease or leprosy.

1H-IMIDAZO[4,5-c]QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of imidazoquinolines and salts thereof in the treatment of protein kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases, imidazoquinolines for use in the treatment of protein kinase dependent diseases, a method of treatment against said diseases, comprising administering the imidazoloquinolines to a warm-blooded animal, especially a human, pharmaceutical preparations comprising an imidazoquinoline, especially for the treatment of a protein kinase dependent disease, novel imidazoquinolines, and a process for the preparation of the novel imidazoquinolines.