The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.
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Paragraph 0366
(2016/12/01)
METALLO-BETA-LACTAMASE INHIBITORS
The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.
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Page/Page column 61
(2015/08/06)
Oximes and hydrazones that are useful in treating sexual dysfunction
The present invention relates to oximes and hydrazones of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
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Page/Page column 42
(2010/02/13)
Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists
A series of 3-aryl piperidine analogs with 2-piperidinoalkylamino or 2-piperidinoalkyloxy fused bicyclic rings were prepared and found to be potent and efficacious human dopamine D4 agonists. The synthesis and structure-activity relationship (SAR) studies that led to the identification of these compounds are discussed.
Wang, Xueqing,Bhatia, Pramila A.,Daanen, Jerome F.,Latsaw, Steve P.,Rohde, Jeffrey,Kolasa, Teodozyi,Hakeem, Ahmed A.,Matulenko, Mark A.,Nakane, Masaki,Uchic, Marie E.,Miller, Loan N.,Chang, Renjie,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.
p. 4667 - 4678
(2007/10/03)
Acetamides and benzamides that are useful in treating sexual dysfunction
The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
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(2008/06/13)
Acetamides and benzamides that are useful in treating sexual dysfunction
The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
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Page 123
(2008/06/13)
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