Convenient Synthesis of 3-Methyl-1-(4-pyridinyl)-2-butanone using Phenyllithium as a Metalating Agent
3-Methyl-1-(4-pyridinyl)-2-butanone has been synthesized via a short and convenient method based upon acylation of 4-picoline by phenyllithium followed by reaction with ethyl isobutyrate.This procedure can be extendet to the preparation of various alkyl pyridyl ketones, intermediates in the synthesis of potential antitumor 6-substituted 7H-pyridocarbazole dimers.
Leon, P.,Garbay-Jaureguiberry, C.,Roques, B. P.
p. 1547 - 1550
(2007/10/02)
More Articles about upstream products of 6304-29-6