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63250-09-9

2,3-DINOR THROMBOXANE B2, also known as 2,3-dinor TXB2, is a significant urinary metabolite of Thromboxane B2 (TXB2). It is released in substantial quantities from aggregating platelets and is metabolized during circulation to 11-dehydro TXB2. As an abundant urinary metabolite, 2,3-dinor TXB2 serves as a reliable marker for in vivo TXA2 synthesis. In healthy male volunteers, the median excretion of 2,3-dinor TXB2 is 10.3 ng/hour (138 pg/mg creatine).

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  • 3-Pentenoic acid,5-[(2R,3S,4S,6R)-tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2H-pyran-3-yl]-,(3Z)-

    Cas No: 63250-09-9

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  • 3-Pentenoic acid,5-[(2R,3S,4S,6R)-tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2H-pyran-3-yl]-,(3Z)-

    Cas No: 63250-09-9

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  • 63250-09-9 Structure

  • Basic information

    1. Product Name: 2,3-DINOR THROMBOXANE B2
    2. Synonyms: 2,3-DINOR-TXB2;2,3-DINOR THROMBOXANE B2;9ALPHA,11,15S-TRIHYDROXY-2,3-DINOR-THROMBA-5Z,13E-DIEN-1-OIC ACID;(E)-5-[(2S,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]pent-3-enoic acid;(5Z,13E,15S)-9α,11,15-Trihydroxy-2,3-dinorthromboxa-5,13-dien-1-oic acid;2,3-dinor Thromboxane B2 Lipid Maps MS Standard;RJHNVFKNIJQTQF-LMIBIYGPSA-N
    3. CAS NO:63250-09-9
    4. Molecular Formula: C18H30O6
    5. Molecular Weight: 342.43
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 63250-09-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 566.9°C at 760 mmHg
    3. Flash Point: 199.5°C
    4. Appearance: /
    5. Density: 1.209g/cm3
    6. Vapor Pressure: 3.25E-15mmHg at 25°C
    7. Refractive Index: 1.571
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2,3-DINOR THROMBOXANE B2(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,3-DINOR THROMBOXANE B2(63250-09-9)
    12. EPA Substance Registry System: 2,3-DINOR THROMBOXANE B2(63250-09-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 63250-09-9(Hazardous Substances Data)

63250-09-9 Usage

Uses

Used in Medical Research:
2,3-DINOR THROMBOXANE B2 is used as a biomarker for [application reason] to monitor and assess in vivo TXA2 synthesis. This is particularly important in understanding platelet aggregation and related physiological processes.
Used in Pharmaceutical Industry:
2,3-DINOR THROMBOXANE B2 is used as a research tool for [application reason] in the development of drugs targeting platelet aggregation and related conditions. Its role as a biomarker allows for the evaluation of drug efficacy and potential therapeutic effects on TXA2 synthesis.
Used in Diagnostics:
2,3-DINOR THROMBOXANE B2 is used as a diagnostic indicator for [application reason] in identifying and monitoring conditions related to platelet aggregation and TXA2 synthesis. This can be particularly useful in the assessment of cardiovascular and thrombotic disorders.
Used in Clinical Trials:
2,3-DINOR THROMBOXANE B2 is used as an endpoint measurement for [application reason] in clinical trials evaluating the effects of new drugs or therapies on platelet aggregation and TXA2 synthesis. Its role as a biomarker provides a quantifiable and reliable method for assessing treatment outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 63250-09-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,2,5 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63250-09:
(7*6)+(6*3)+(5*2)+(4*5)+(3*0)+(2*0)+(1*9)=99
99 % 10 = 9
So 63250-09-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H30O6/c1-2-3-4-7-13(19)10-11-16-14(8-5-6-9-17(21)22)15(20)12-18(23)24-16/h5-6,10-11,13-16,18-20,23H,2-4,7-9,12H2,1H3,(H,21,22)/b6-5-,11-10+/t13-,14?,15-,16+,18+/m0/s1

63250-09-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-DINOR THROMBOXANE B2

1.2 Other means of identification

Product number -
Other names 2,3-DINOR-TXB2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63250-09-9 SDS

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