63331-62-4Relevant articles and documents
A Rapid and Efficient Synthesis of Sulfur Analogues of Pyrimidine Bases
Lapucha, Andrzej R.
, p. 256 - 258 (2007/10/02)
An improved procedure for thionation of some natural pyrimidine bases with tetraphosphorus decasulfide/sodium hydrogen carbonate is reported.Some substituted uracils and 2-thiouracils were converted into a series of analogues in which the oxygen at position 4 was replaced by sulfur atom.The advantage of this method of thionation over the older procedures is based on the tetraphosphorus decasulfide/sodium hydrogen carbonate mixture giving rise to excellent yields and simplified isolation of the desired pure products.