Synthesis of N-substituted-N-acylthioureas of 4-substituted piperazines endowed with local anaesthetic, antihyperlipidemic, antiproliferative activities and antiarrythmic, analgesic, antiaggregating actions
Three series of N-acyl and N-cyclohexyl- or N-methyl or N-phenyl-thioureas of 4-substituted (methyl, phenyl, 2-pyridyl)piperazines (4-12) were synthesised according to a highly convergent one-pot procedure and tested in vivo (local anaesthetic, anti-hyper
A New Convenient Method of Desulphurisation of Thioureas and Thioamides
The action of thiophosgene on thioureas and thioamides provides a convenient method of desulphurisation of these compounds to ureas and amides respectively.
Abuzar, Syed,Sharma, Satyavan,Iyer, R. N.
p. 211 - 212
(2007/10/02)
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