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3-Fluoro-5-Trifluoromethylbenzyl Chloride is a specialty chemical compound that belongs to the benzyl chloride family. It is characterized by a benzene ring with a chloromethane group attached, featuring a fluorine atom at the 3-position and a trifluoromethyl group at the 5-position. This unique structure endows the compound with specific reactivity and selectivity in organic synthesis, particularly in the pharmaceutical industry. As a fluorinated compound, it is instrumental in introducing fluorine groups into drug molecules, which can improve their metabolic stability and bioavailability.

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  • 634151-25-0 Structure
  • Basic information

    1. Product Name: 3-FLUORO-5-TRIFLUOROMETHYLBENZYL CHLORIDE
    2. Synonyms: 1-(ChloroMethyl)-3-fluoro-5-(trifluoroMethyl)benzene;Benzene,1-(chloromethyl)-3-fluoro-5-(trifluoromethyl)-;3-FLUORO-5-TRIFLUOROMETHYLBENZYL CHLORIDE
    3. CAS NO:634151-25-0
    4. Molecular Formula: C8H5ClF4
    5. Molecular Weight: 212.5719128
    6. EINECS: N/A
    7. Product Categories: Fluorine series
    8. Mol File: 634151-25-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 171.2 °C at 760 mmHg
    3. Flash Point: 67.2 °C
    4. Appearance: /
    5. Density: 1.372 g/cm3
    6. Vapor Pressure: 1.89mmHg at 25°C
    7. Refractive Index: 1.442
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 3-FLUORO-5-TRIFLUOROMETHYLBENZYL CHLORIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-FLUORO-5-TRIFLUOROMETHYLBENZYL CHLORIDE(634151-25-0)
    12. EPA Substance Registry System: 3-FLUORO-5-TRIFLUOROMETHYLBENZYL CHLORIDE(634151-25-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 634151-25-0(Hazardous Substances Data)

634151-25-0 Usage

Uses

Used in Pharmaceutical Industry:
3-Fluoro-5-Trifluoromethylbenzyl Chloride is used as an intermediate in organic synthesis for the development of pharmaceutical compounds. Its unique structure allows for the introduction of fluorine groups into drug molecules, which can enhance their metabolic stability and bioavailability, making them more effective in medical applications.
Used in Organic Synthesis:
In the field of organic synthesis, 3-Fluoro-5-Trifluoromethylbenzyl Chloride is used as a key building block for the creation of complex molecules. Its reactivity and selectivity make it a valuable component in the synthesis of various organic compounds, including those with potential applications in materials science, agrochemicals, and specialty chemicals.
Safety Precautions:
Due to the nature of 3-Fluoro-5-Trifluoromethylbenzyl Chloride, it is essential to handle this chemical with care to prevent harm or risk of exposure. Proper safety measures, such as wearing protective gear and working in a controlled environment, should be taken to ensure the safe handling and use of this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 634151-25-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,4,1,5 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 634151-25:
(8*6)+(7*3)+(6*4)+(5*1)+(4*5)+(3*1)+(2*2)+(1*5)=130
130 % 10 = 0
So 634151-25-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H5ClF4/c9-4-5-1-6(8(11,12)13)3-7(10)2-5/h1-3H,4H2

634151-25-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(Chloromethyl)-3-fluoro-5-(trifluoromethyl)benzene

1.2 Other means of identification

Product number -
Other names 1-(chloromethyl)-3-fluoro-5-(trifluoromethyl)benzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:634151-25-0 SDS

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