634583-91-8

Basic information

• Product Name: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(methylamino)-2-oxo- (9CI)
• Synonyms: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(methylamino)-2-oxo- (9CI)
• CAS NO: 634583-91-8
• Molecular Formula: C7H7N3O
• Molecular Weight: 149.14998
• Product Categories: PYRIDINE;ALCOHOL
• Mol File: 634583-91-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(methylamino)-2-oxo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(methylamino)-2-oxo- (9CI)(634583-91-8)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(methylamino)-2-oxo- (9CI)(634583-91-8)

Safety Data

• Hazardous Substances Data: 634583-91-8(Hazardous Substances Data)

Upstream product

• 360062-13-1 α-cyano-β-(N-methylamino)crotonic acid amide 
• 634583-90-7 5-cyano-1,6-dimethyl-1,4-dihydro-4-pyrimidinone 
• 120651-05-0 α-cyano-β-dimethylaminocrotonamide 

Relevant articles and documents

Synthesis and chemical conversions of 2-chloro-3-cyano-4-methylamino-5-nitropyridine

5-Cyano-6-(β-dimethylamino)vinyl-1-methyl-4-pyrimidinone was synthesized by the interaction of α-cyano-β-(N-methylamino)crotonamide with N,N-dimethylformamide diethylacetal. Recyclization of the product in alkaline medium leads to 3-cyano-4-methylamino-2-pyridone. Nitration of the latter and transformation of the nitropyridone by boiling in POCl3 gave 2-chloro-3-cyano-4-methylamino-5-nitropyridine. This is a key compound for various transformations including the synthesis of derivatives of dipyrido[1,2-a:3,2-e]pyrimidine, thieno[2,3-b]pyridine, and (2-pyridylamino)polyene derivatives.