635318-20-6Relevant articles and documents
Synthesis and pharmacological characterization of 4-substituted-2- aminobicyclo[3.1.0]hexane-2,6-dicarboxylates: Identification of new potent and selective metabotropic glutamate 2/3 receptor agonists
Monn, James A.,Valli, Matthew J.,Massey, Steven M.,Hao, Junliang,Reinhard, Matthew R.,Bures, Mark G.,Heinz, Beverly A.,Wang, Xushan,Carter, Joan H.,Getman, Brian G.,Stephenson, Gregory A.,Herin, Marc,Catlow, John T.,Swanson, Steven,Johnson, Bryan G.,McKinzie, David L.,Henry, Steven S.
, p. 4442 - 4455 (2013/07/19)
As part of our ongoing interest in identifying novel agonists acting at metabotropic glutamate (mGlu) 2/3 receptors, we have explored the effect of structural modifications of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6- dicarboxylate (LY354740), a potent
A method for the synthesis of 2-amino-4-fluorobicyclo[3.1.0]hexane-2,6- dicarboxylic acid-[3H2]
Kuo, Fengjiun,Kulanthaivel, Palaniappan,Rener, Gregory A.,Yi, Ping,Wheeler, William J.
, p. 571 - 581 (2007/10/03)
A process for double deuterium labeling of an alcohol was developed. The process was utilized in the subsequent tritium labeling of a secondary alcohol with high specific activity (24 Ci/mmol) by reduction of the corresponding ketone using sodium borotrit
PRODRUGS OF EXCITATORY AMINO ACIDS
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Page 110, (2008/06/13)
This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorder