63647-04-1

Basic information

• Product Name: [2-(1H-pyrrol-1-yl)thien-3-yl]methylamine
• Synonyms: [2-(1H-pyrrol-1-yl)thien-3-yl]methylamine
• CAS NO: 63647-04-1
• Molecular Formula: C9H10N2S
• Molecular Weight: 178.25
• Mol File: 63647-04-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [2-(1H-pyrrol-1-yl)thien-3-yl]methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(1H-pyrrol-1-yl)thien-3-yl]methylamine(63647-04-1)
• EPA Substance Registry System: [2-(1H-pyrrol-1-yl)thien-3-yl]methylamine(63647-04-1)

Safety Data

• Hazardous Substances Data: 63647-04-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
[2-(1H-pyrrol-1-yl)thien-3-yl]methylamine is used as a pharmaceutical intermediate for the development of new compounds with potential therapeutic applications. Its unique structure and biological activity make it a promising candidate for the creation of novel drugs targeting various medical conditions.
Used in Organic Synthesis:
In the field of organic synthesis, [2-(1H-pyrrol-1-yl)thien-3-yl]methylamine is used as a key building block for constructing complex organic molecules. Its versatile structure allows for the synthesis of a wide range of functional materials with diverse applications in various industries.
Used in Medicinal Chemistry:
PTMA is employed as a valuable component in medicinal chemistry, where it contributes to the design and synthesis of new drugs with improved efficacy and selectivity. Its incorporation into drug candidates can potentially enhance their pharmacological properties and therapeutic potential.

Relevant articles and documents

Pyrrolo [1,2A] thieno [3,2-F] [1,4] diazepines

The invention relates to pyrrolo [1,2-a] thieno [3,2-f][1,4]diazepine compounds of the formula (I) STR1 in which: R1 is hydrogen; alkyl optionally substituted with alkoxy, hydroxy, cycloalkyl, or phenyl; or alkyl- or arylsulfonyl; R2 is hydrogen, phenyl, or phenylalkyl; alkyl optionally substituted with hydroxyl, alkoxy, oxo, cycloalkyl or phenyl; or optionally substituted amino; R3 represents hydrogen or alkyl, and R4 and R5 independently represent: hydrogen, alkyl optionally substituted with alkoxy, cycloalkyl, or phenyl; or phenyl; their isomers, diastereoisomers and enantiomers as well as their addition salts with pharmaceutically-acceptable acids. The compounds are useful for treating cerebral ischemia, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia, and hyperglycemia and are obtained in a few steps from the corresponding substituted 2-(1-pyrrolyl)thiophenes STR2 Y=--CHO or H; X= CN, CONH2, CH2 NHCOR2, or CH2 NH2.