637020-80-5

Basic information

• Product Name: (R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL
• Synonyms: (R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL;(R)-a-(3-Chlorobenzyl)proline·HCl;(R)-a-(3-chloro-benzyl)-prolineCl;L-Proline,2-[(3-chlorophenyl)Methyl]-;2-[(3-chlorophenyl)methyl]-L-Proline;(R)-Alpha-(3-chloro-benzyl)-ProHCl
• CAS NO: 637020-80-5
• Molecular Formula: C12H15Cl2NO2
• Molecular Weight: 276.16
• Mol File: 637020-80-5.mol

Chemical Properties

• Boiling Point: 390.3 °C at 760 mmHg
• Flash Point: 189.8 °C
• Appearance: /
• Vapor Pressure: 8.63E-07mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL(637020-80-5)
• EPA Substance Registry System: (R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL(637020-80-5)

Safety Data

• Hazardous Substances Data: 637020-80-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
(R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL is used as a precursor or intermediate in the synthesis of pharmaceuticals and other biologically active compounds. Its role in this industry is pivotal for the development of new drugs, as it aids in understanding the relationship between molecular structure and biological activity, which is essential for optimizing drug efficacy and safety.
Used in Structure-Activity Relationship Studies:
In the field of medicinal chemistry, (R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL is employed as a key component in studies aimed at elucidating the structure-activity relationship of proline-containing compounds. This helps researchers to identify the necessary structural features for biological activity, thereby guiding the design of more effective and selective drugs.
Used in Drug Design and Optimization:
(R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL is utilized in the design and optimization of drug candidates, particularly those that involve proline as a key structural element. Its unique 3-chlorobenzyl group allows for the probing of interactions with biological targets, which can lead to the discovery of compounds with improved pharmacological properties, such as increased potency, selectivity, and reduced side effects.
Used in Biological Target Interaction Studies:
In the broader scope of biological research, (R)-ALPHA-(3-CHLOROBENZYL)-PROLINE-HCL is used to explore the interactions of proline-based molecules with various biological targets. This can provide insights into the mechanisms of action of these compounds and inform the development of targeted therapies for a range of diseases and conditions.

InChI:InChI=1/C12H14ClNO2.ClH/c13-10-4-1-3-9(7-10)8-12(11(15)16)5-2-6-14-12;/h1,3-4,7,14H,2,5-6,8H2,(H,15,16);1H/t12-;/m1./s1