638192-65-1

Basic information

• Product Name: 5-Benzoxazolecarboxaldehyde (9CI)
• Synonyms: 5-Benzoxazolecarboxaldehyde (9CI);benzo[d]oxazole-5-carbaldehyde;1,3-Benzoxazole-2,5-dicarbaldehyde;5-Benzoxazolecarboxaldehyde;1,3-Benzoxazole-5-carbaldehyde
• CAS NO: 638192-65-1
• Molecular Formula: C8H5NO2
• Molecular Weight: 147.1308
• Product Categories: ALDEHYDE
• Mol File: 638192-65-1.mol

Chemical Properties

• Boiling Point: 359.3°C at 760 mmHg
• Flash Point: 171.1°C
• Appearance: /
• Density: 1.425g/cm³
• Vapor Pressure: 2.4E-05mmHg at 25°C
• Refractive Index: 1.709
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -2.52±0.10(Predicted)
• CAS DataBase Reference: 5-Benzoxazolecarboxaldehyde (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzoxazolecarboxaldehyde (9CI)(638192-65-1)
• EPA Substance Registry System: 5-Benzoxazolecarboxaldehyde (9CI)(638192-65-1)

Safety Data

• Hazardous Substances Data: 638192-65-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
5-Benzoxazolecarboxaldehyde (9CI) is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, leveraging its unique chemical properties to create a range of bioactive compounds.
Used in Organic Synthesis:
As a key intermediate, 5-Benzoxazolecarboxaldehyde (9CI) is employed in the synthesis of organic compounds, contributing to the development of new chemical entities with potential applications in various fields.
Used as a Fluorescent Dye in Biological and Chemical Applications:
5-Benzoxazolecarboxaldehyde (9CI) is utilized as a fluorescent dye in both biological and chemical applications, taking advantage of its optical properties to enhance imaging and detection processes.

InChI:InChI=1/C9H5NO3/c11-4-6-1-2-8-7(3-6)10-9(5-12)13-8/h1-5H

Upstream product

• 15112-41-1 1,3-benzoxazol-5-carboxylic acid 
• 1488698-24-3 benzo[d]oxazol-5-ylmethanol 
• 1622428-38-9 5-vinylbenzo[d]oxazole 
• 132244-31-6 5-bromo-1,3-benzoxazole 
• 40925-68-6 2-amino-4-bromo-phenol 

Relevant articles and documents

3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF

The present disclosure relates to compounds of formula (I') and pharmaceutical compositions and their use in reducing Widely Interspaced Zinc Finger Motifs (WIZ) expression levels, or inducing fetal hemoglobin (HbF) expression, and in the treatment of inherited blood disorders (e.g., hemoglobinopathies, e.g., beta-hemoglobinopathies), such as sickle cell disease and beta-thalassemia.

GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS

The present disclosure provides γ-diketones or analogs thereof, that activate Wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries or spine injuries, brain atrophy/neurological disorders related to the differentiation and development of the central nervous system, including Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; otic disorders like cochlear hair cell loss; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, such as hair loss, hematopoiesis related diseases and tissue regeneration related diseases.