- An anthraquinone derivative from Cassia grandis Linn.
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An anthraquinone derivative, 1,5-dihydroxy-8-methoxy-2,3-dimethyl-9,10-anthraquinone (1) has been isolated from ethyl acetate extract of the root bark of Cassia grandis (Leguminosae) and characterized by spectral and chemical analyses. This is the first report of isolation and characterisation of this compound.
- Ambasta,Prasad,Sinha,Verma
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p. 990 - 991
(2007/10/03)
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- Pharmaceutical compounds
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Pharmaceutical compounds of the formula STR1 in which R1 and R2 are each hydrogen, hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, --O-glucoside, optionally substituted phenyl or optionally substituted phenyl-C1-4 alkoxy; R3 is tetrazolyl, or and R4 and R5 are each hydrogen, hydroxy, acyloxy, nitro, C1-4 alkyl, C1-4 alkoxy, halo, optionally substituted phenyl, --SO3 H or --NR'R" where R' and R" are each hydrogen or C1-4 alkyl; provided that when R3 is --CR'R".CHR'"CO2 H or tetrazolyl, R1 and R2 are each hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, --O-glucoside, optionally substituted phenyl or optionally substituted phenyl C1-4 alkoxy; and or a pharmaceutically acceptable salt or ester thereof.
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- Thiol-reactive Fluorescent probes for Protein Labelling
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Cyclisation of N-alkylmaleic acids mediated by acetic anhydride in dimethylacetamide in the presence of traces of cobalt naphthenate has been used for efficient assembly of a range of fluorescent maleimide reagents.The fluorescence responses of these reagents to addition of thiol across the maleimide double bond, and to hydrolysis of the meleimide ring, are described.
- Corrie, John E. T.
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p. 2975 - 2982
(2007/10/02)
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- Aromatic prostaglandin derivatives
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Aromatic prostaglandin derivatives are prepared. These compounds have valuable antiprostaglandin activity specifically inhibiting prostaglandin synthesis and antagonizing diarrhea induced by prostaglandin E2 (PGE2).
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