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Cardiolipin is a glycerophospholipid that is predominantly found in the inner mitochondrial membrane. It plays a crucial role in maintaining the structural integrity and function of the mitochondria. Cardiolipin possesses unique structural features, including two glycerol backbones, four fatty acid chains, and two phosphate groups. These features enable it to interact with various proteins and enzymes, making it an essential component of cellular metabolism and energy production.

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  • 64043-42-1 Structure
  • Basic information

    1. Product Name: Cardiolipin
    2. Synonyms:
    3. CAS NO:64043-42-1
    4. Molecular Formula: C73H140O17P2.2Na
    5. Molecular Weight: 1397.82
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 64043-42-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Cardiolipin(CAS DataBase Reference)
    10. NIST Chemistry Reference: Cardiolipin(64043-42-1)
    11. EPA Substance Registry System: Cardiolipin(64043-42-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 64043-42-1(Hazardous Substances Data)

64043-42-1 Usage

Uses

Used in Pharmaceutical Industry:
Cardiolipin is used as a biological marker for indicating pathological states. Its levels can be monitored to assess mitochondrial dysfunction and oxidative stress, which are often associated with various diseases, including neurodegenerative disorders, cardiovascular diseases, and cancer.
Used in Diagnostic Applications:
Cardiolipin is used as a diagnostic tool to detect and monitor mitochondrial dysfunction in various diseases. Its analysis can provide valuable insights into the underlying mechanisms of the disease and help in the development of targeted therapies.
Used in Drug Development:
Cardiolipin can be used in the development of drugs targeting mitochondrial function. Its unique interactions with proteins and enzymes make it a promising candidate for the design of novel therapeutic agents that can modulate mitochondrial activity and improve cellular metabolism.
Used in Nutritional Supplements:
Cardiolipin can be used as a nutritional supplement to support mitochondrial health and function. Its supplementation may help improve energy production, reduce oxidative stress, and support overall health and well-being.

Check Digit Verification of cas no

The CAS Registry Mumber 64043-42-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,4 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64043-42:
(7*6)+(6*4)+(5*0)+(4*4)+(3*3)+(2*4)+(1*2)=101
101 % 10 = 1
So 64043-42-1 is a valid CAS Registry Number.

64043-42-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-di(1,2-dipalmitoyl-sn-glycero-3-phospho)glycerol sodium salt

1.2 Other means of identification

Product number -
Other names 1.3-Bis-O-(di-O-palmitoyl-DL-α-glyceryl-phosphoryl)glycerin-dinatriumsalz

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:64043-42-1 SDS

64043-42-1Downstream Products

64043-42-1Relevant articles and documents

A Short, Flexible Route to Symmetrically and Unsymmetrically Substituted Diphoshatidyglycerols (Cardiolipins)

Keana, John F. W.,Shimizu, Masato,Jernstedt, Karen K.

, p. 2297 - 2299 (2007/10/02)

Phosphatidyglycerol methyl esters 2a,b undergo selective phosphorylation on the primary alcohol with phosphatidic acid 3a to give, after methylation of the crude product for purposes of purification and then didemethylation, symmetrically substituted DPG 5a and unsymmetrically substituted DPG 5b, respectively, in moderate overall yield.

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