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641-39-4

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Synthesis and biological evaluation of nitric oxide-releasing matrine derivatives as anticancer agents
A series of furoxan-based nitric oxide-releasing matrine derivatives (10a-f) were synthesized. The biological evaluation showed that compounds 10a, 10b, 10e and 10f had stronger cytotoxic activities than 5-fluorouracil against human hepatoma cells (HepG2) in vitro.
He, Li Qin,Liu, Jing,Yin, Deng Ke,Zhang, Yi Hua,Wang, Xiao Shan
scheme or table
p. 381 - 384
(2010/12/25)

The alkaloid constituents of Euchresta japonica and the stereochemical assignment of two isomeric sophoridine N-oxides
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Ohmiya,Otomasu,Haginiwa,Murakoshi
p. 546 - 551
(2007/10/02)

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Chemical Properties

Melting Point: 106-107 °C
Boiling Point: 396.738 °C at 760 mmHg
Flash Point:172.748 °C
Density: 1.164 g/cm³
PKA: 9.47±0.20(Predicted)
PSA: 66.84000
LogP: 2.22390

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