64169-57-9

Basic information

• Product Name: CHLOROCITALOPRAM
• Synonyms: CHLOROCITALOPRAM;1-(4-CHLORO-PHENYL)-1-(3-DIMETHYLAMINO-PROPYL)-1,3-DIHYDRO-ISOBENZOFURAN-5-CARBONITRILE
• CAS NO: 64169-57-9
• Molecular Formula: C20H21ClN2O
• Molecular Weight: 340.85
• Product Categories: Drug Analogues
• Mol File: 64169-57-9.mol

Chemical Properties

• Boiling Point: 452.4°C at 760 mmHg
• Flash Point: 227.4°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 2.25E-08mmHg at 25°C
• Refractive Index: 1.61
• Solubility: Chloroform, Methanol
• CAS DataBase Reference: CHLOROCITALOPRAM(CAS DataBase Reference)
• NIST Chemistry Reference: CHLOROCITALOPRAM(64169-57-9)
• EPA Substance Registry System: CHLOROCITALOPRAM(64169-57-9)

Safety Data

• Hazardous Substances Data: 64169-57-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
CHLOROCITALOPRAM is used as an internal standard for the antidepressant drug Citalopram, which is prescribed for the treatment of depression and anxiety disorders. As an internal standard, it helps in the accurate quantification of Citalopram in various pharmaceutical formulations, ensuring the consistency and efficacy of the drug.
Used in Research and Development:
In the field of research and development, CHLOROCITALOPRAM is utilized as a reference compound for the study of serotonin reuptake inhibition. This helps scientists and researchers understand the mechanisms of action of antidepressant drugs and develop new, more effective treatments for mood disorders.
Used in Quality Control and Analysis:
CHLOROCITALOPRAM is also employed in the quality control and analysis of pharmaceutical products containing Citalopram. It serves as a benchmark for the assessment of the drug's purity, potency, and stability, ensuring that the final product meets the required standards for safety and efficacy.

InChI:InChI=1/C20H21ClN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3

Relevant articles and documents

Anti-depressive substituted 1-dimethylaminopropyl-1-phenyl phthalans

The present invention relates to phthalans of the following general formula: STR1 wherein R1 and R2 each represents halogen, a trifluoromethyl group, a cyano group or R--CO-- wherein R is an alkyl-radical with from 1-4 C-atoms inclusive, as well as acid addition salts thereof with pharmaceutically acceptable acids.