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CAS

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643044-24-0

2(1H)-Pyridinone,3-isocyanato-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 643044-24-0 Structure

  • Basic information

    1. Product Name: 2(1H)-Pyridinone,3-isocyanato-(9CI)
    2. Synonyms: 2(1H)-Pyridinone,3-isocyanato-(9CI)
    3. CAS NO:643044-24-0
    4. Molecular Formula: C6H4N2O2
    5. Molecular Weight: 136.10816
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 643044-24-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2(1H)-Pyridinone,3-isocyanato-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2(1H)-Pyridinone,3-isocyanato-(9CI)(643044-24-0)
    11. EPA Substance Registry System: 2(1H)-Pyridinone,3-isocyanato-(9CI)(643044-24-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 643044-24-0(Hazardous Substances Data)

643044-24-0 Usage

Derived from

Pyridine

Contains

Isocyanate functional group

Potential to react with

Various organic compounds, particularly nucleophiles

Use as

Building block in the synthesis of various organic compounds and materials (pharmaceuticals, polymers, agrochemicals)

Useful in

A variety of chemical processes and applications

Check Digit Verification of cas no

The CAS Registry Mumber 643044-24-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,3,0,4 and 4 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 643044-24:
(8*6)+(7*4)+(6*3)+(5*0)+(4*4)+(3*4)+(2*2)+(1*4)=130
130 % 10 = 0
So 643044-24-0 is a valid CAS Registry Number.

643044-24-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-isocyanato-2(1H)-pyridinone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:643044-24-0 SDS

643044-24-0Downstream Products

643044-24-0Relevant articles and documents

New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists

Yea, Christopher M.,Allan, Christine E.,Ashworth, Doreen M.,Barnett, James,Baxter, Andy J.,Broadbridge, Janice D.,Franklin, Richard J.,Hampton, Sally L.,Hudson, Peter,Horton, John A.,Jenkins, Paul D.,Penson, Andy M.,Pitt, Gary R. W.,Rivière, Pierre,Robson, Peter A.,Rooker, David P.,Semple, Graeme,Sheppard, Andy,Haigh, Robert M.,Roe, Michael B.

scheme or table, p. 8124 - 8134 (2009/11/30)

Vasopressin (AVP) is a hormone that stimulates an increase in water permeability through activation of V2 receptors in the kidney. The analogue of AVP, desmopressin, has proven an effective drug for diseases where a reduction of urine output is desired. However, its peptidic nature limits its bioavailability. We report herein the discovery of potent, nonpeptidic, benzylurea derived agonists of the vasopressin V2 receptor. We describe substitutions on the benzyl group to give improvements in potency and subsequent modifications to the urea end group to provide improvements in solubility and increased oral efficacy in a rat model of diuresis. The lead compound 20e (VA106483) is reported for the first time and has been selected for clinical development.

SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS

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Page 135-136, (2010/02/06)

The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b), enantiomers, diastereomers, salts and solvates thereof wherein R1, R2, R3, R4, R5, and R7 are as defined herein. The invention further includes a method of CCR5-mediated

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