643751-48-8

Basic information

• Product Name: 3a-hydroxy-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester
• Synonyms: 3a-hydroxy-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester
• CAS NO: 643751-48-8
• Molecular Weight: 368.389
• Mol File: 643751-48-8.mol

Chemical Properties

• CAS DataBase Reference: 3a-hydroxy-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3a-hydroxy-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester(643751-48-8)
• EPA Substance Registry System: 3a-hydroxy-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester(643751-48-8)

Safety Data

• Hazardous Substances Data: 643751-48-8(Hazardous Substances Data)

Upstream product

• 7432-21-5 N-carbobenzyloxy-L-tryptophane 
• 643751-44-4 3a-phenylselanyl-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,2,8-tricarboxylic acid 1-benzyl ester 8-tert-butyl ester 2-methyl ester 
• 643751-42-2 N-carbobenzyloxy-1-tert-butoxycarbonyl-L-tryptophan methyl ester 
• 2717-76-2 (S)-N-benzyloxycarbonyl-L-tryptophan methyl ester 
• 643751-46-6 3a-hydroxy-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,2,8-tricarboxylic acid 1-benzyl ester 8-tert-butyl ester 2-methyl ester 

Downstream Products

• 108431-24-9 (3S,5aS,10bR,11aS)-3-Benzyl-10b-hydroxy-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione 
• 1054626-88-8 (2S,3aR,8aS)-1-((S)-2-Benzyloxycarbonylamino-propionyl)-3a-hydroxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid methyl ester 
• 1053740-72-9 (2S,3aR,8aS)-1-((S)-2-Benzyloxycarbonylamino-3-methyl-butyryl)-3a-hydroxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid methyl ester 
• 1054630-85-1 (2S,3aR,8aS)-1-((S)-2-Benzyloxycarbonylamino-3-hydroxy-propionyl)-3a-hydroxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid methyl ester 
• 1054604-07-7 (2S,3aR,8aS)-1-((S)-1-Benzyloxycarbonyl-pyrrolidine-2-carbonyl)-3a-hydroxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid methyl ester 
• 1055042-09-5 (2S,3aR,8aS)-1-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionyl)-3a-hydroxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid methyl ester 
• 1054609-54-9 (2S,3aR,8aS)-1-((2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyryl)-3a-hydroxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid methyl ester 
• 1053271-19-4 (2S,3aR,8aS)-1-[(S)-2-Benzyloxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionyl]-3a-hydroxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid methyl ester 

Relevant articles and documents

A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo[2,3-b]indole skeleton, a building block for 10b-hydroxypyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole-1,4-diones

A study was performed on the rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo-[2,3-b]indole skeleton. A two-step selenocyclisation-oxidative deselenation sequence was used for the synthesis. It is reported that many biologically active natural products are based on this structure, such as the sporidesmins and certain members of the brevianamide and okaramine families.