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Pyridine iodine monochloride complex, also known as iodine monochloride pyridine complex, is a chemical compound formed by the reaction of pyridine with iodine monochloride. It is a yellowish crystalline solid that is typically synthesized by reacting pyridine with iodine monochloride in a chlorinated solvent. This complex is recognized for its mild electrophilic iodinating properties and its ability to efficiently iodinate electron-rich aromatic systems, making it a valuable tool in the field of synthetic chemistry.

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  • 6443-90-9 Structure
  • Basic information

    1. Product Name: PYRIDINE IODINE MONOCHLORIDE COMPLEX
    2. Synonyms: PYRIDINE IODINE MONOCHLORIDE COMPLEX;Iodinemonochloride,compd.withpyridine(1:1);Pyridine,compd.withiodinechloride(ICl)(1:1);Chloroiodane pyridine methane;Pyridinium iodochloride;Pyridine Iodine Monochloride
    3. CAS NO:6443-90-9
    4. Molecular Formula: C5H5ClIN
    5. Molecular Weight: 241.46
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 6443-90-9.mol
  • Chemical Properties

    1. Melting Point: 133.0 to 137.0 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C Freezer
    8. Solubility: Acetone (Slightly), Methanol (Slightly)
    9. CAS DataBase Reference: PYRIDINE IODINE MONOCHLORIDE COMPLEX(CAS DataBase Reference)
    10. NIST Chemistry Reference: PYRIDINE IODINE MONOCHLORIDE COMPLEX(6443-90-9)
    11. EPA Substance Registry System: PYRIDINE IODINE MONOCHLORIDE COMPLEX(6443-90-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 6443-90-9(Hazardous Substances Data)

6443-90-9 Usage

Uses

Used in Organic Synthesis:
Pyridine iodine monochloride complex is used as a mild electrophilic iodinating agent for the iodination of aromatic compounds. It is favored for its good regioselectivity and efficiency in iodinating electron-rich aromatic systems.
Used in the Synthesis of Iodinated Organic Compounds:
In the field of organic chemistry, the complex serves as a reagent for the synthesis of various iodinated organic compounds, contributing to the preparation of diverse organic intermediates.
Used in the Oxidation of Organic Compounds:
Pyridine iodine monochloride complex is also utilized as a reagent for the oxidation of organic compounds, further expanding its applications in synthetic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 6443-90-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,4 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6443-90:
(6*6)+(5*4)+(4*4)+(3*3)+(2*9)+(1*0)=99
99 % 10 = 9
So 6443-90-9 is a valid CAS Registry Number.

6443-90-9 Well-known Company Product Price

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  • TCI America

  • (P2086)  Pyridine Iodine Monochloride  >98.0%(T)

  • 6443-90-9

  • 1g

  • 560.00CNY

  • Detail
  • TCI America

  • (P2086)  Pyridine Iodine Monochloride  >98.0%(T)

  • 6443-90-9

  • 5g

  • 1,950.00CNY

  • Detail

6443-90-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Pyridine Iodine Monochloride

1.2 Other means of identification

Product number -
Other names ICl-pyridine complex

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6443-90-9 SDS

6443-90-9Upstream product

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6443-90-9Relevant articles and documents

Pyridinium lodochloride: An efficient reagent for lodination of hydroxylated aromatic ketones and aldehydes

Khansole, Sandeep V.,Mokle, Shyam S.,Sayyed, Mudassar A.,Vibhute, Yeshwant B.

experimental part, p. 871 - 874 (2009/12/01)

Direct iodination of several reactive aromatic compounds like hydroxy substituted acetophenones and aldehydes with pyridinium iodochloride (PyICl) proceeded smoothly to afford the corresponding aromatic iodides in good to excellent yield. Pyridinium iodochloride has been found to be an efficient solid iodinating reagent with no hazardous effect and it can be handled safely.

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