A total synthesis of (±)-codeine by 1,3-dipolar cycloaddition
Nitrone cycloaddition on a dearomatized bicyclic phenol enabled the facile construction of the correctly configured phenanthrene skeleton of codeine. Further steps yielded allopseudocodeine in a completely diastereoselective manner and finally (±)-codeine by allylic transposition through the hydrolysis of chlorocodides.
Erhard, Thomas,Ehrlich, Gunnar,Metz, Peter
supporting information; experimental part
p. 3892 - 3894
(2011/06/24)
SYNTHESIS OF MORPHINE AND RELATED DERIVATIVES
The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof, wherein the starting compound is biphenyl.
-
Page/Page column 84-85
(2010/12/17)
On the analysis and the stability of codeine phosphate. Part 1: Detection and determination of codeine in the presence of degradation products
-
Gundermann,Pohloudek-Fabini
p. 296 - 299
(2007/10/02)
Process for converting neopinone to codeinone
A process for converting neopinone alkaloid to codeinone alkaloid which involves treating neopinone with a hydrohalic acid in a suitable solvent under anhydrous conditions. It also relates to the compound 8-halodihydrocodeinone hydrohalide.
-
(2008/06/13)
More Articles about upstream products of 64520-25-8