64628-44-0

Basic information

• Product Name: Triflumuron
• Synonyms: triflumuron (bsi,iso), alsystin;BAYSIR;Triflumuron,W.P.;Triflumuron suspension;1-（2-chlorobenzoyl)-3-(4-trifluoromethoxyphenyl) urea;OMS 2015;N-(2-Chlorobenzoyl)-N'-[4-(trifluoromethoxy)phenyl]urea;BAY-8514
• CAS NO: 64628-44-0
• Molecular Formula: C₁₅H₁₀ClF₃N₂O₃
• Molecular Weight: 358.7
• EINECS: 264-980-3
• Product Categories: INSECTICIDE;Alpha sort;Growth regulatorsPesticides&Metabolites;Insecticides;Pesticides;Q-ZAlphabetic;TP - TZ
• Mol File: 64628-44-0.mol

Chemical Properties

• Melting Point: 198℃
• Appearance: /
• Density: 1.475 g/cm³
• Vapor Pressure: 0Pa at 20℃
• Refractive Index: 1.581
• Storage Temp.: 0-6°C
• Solubility: Soluble in DMF
• PKA: 9.79±0.46(Predicted)
• Water Solubility: 40μg/L at 20℃
• BRN: 2776684
• CAS DataBase Reference: Triflumuron(CAS DataBase Reference)
• NIST Chemistry Reference: Triflumuron(64628-44-0)
• EPA Substance Registry System: Triflumuron(64628-44-0)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 2
• RTECS: CV2474000
• Hazardous Substances Data: 64628-44-0(Hazardous Substances Data)

Usage

Uses

Used in Veterinary Medicine:
Triflumuron is used as an insecticide and lousicide for controlling insects pests such as mosquitoes, flies, and sheep body lice (Bovicola ovis). It acts as a chitin synthesis inhibitor, disrupting the exoskeleton formation in insects and effectively controlling their populations.

Flammability and Explosibility

Notclassified

Toxicity evaluation

Acute oral LD50 for rats: >5,000 mg/kg

InChI:InChI=1/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)

Upstream product

• 89-97-4 2-CHLOROBENZYLAMINE 
• 35037-73-1 1-isocyanato-4-trifluoromethoxy-benzene 
• 615-41-8 2-iodochlorobenzene 
• 82971-90-2 1-(4-(trifluoromethoxy)phenyl)urea 
• 82102-37-2 9-methyl-9H-fluorene-9-carbonyl chloride 

Relevant articles and documents

Hydrogen bond directed aerobic oxidation of amines via photoredox catalysis

An application of H-bonding interactions for directing the α-C-H oxidation of amines to amides and amino-ketones catalyzed by an organic photocatalyst is reported. The high efficiency of this method is demonstrated by the aerobic oxidation of pyrrolidines, diarylamines and benzylamines bearing urea groups with high yields and a wide substrate scope.

Palladium-catalyzed N -acylation of monosubstituted ureas using near-stoichiometric carbon monoxide

The palladium-catalyzed carbonylation of urea derivatives with aryl iodides and bromides afforded N-benzoyl ureas (20 examples) in yields attaining quantitative via the application of near-stoichiometric amounts of carbon monoxide generated from the decarbonylation of the CO precursor, 9-methylfluorene-9-carbonyl chloride. The synthetic protocol displayed good functional group tolerance. The methodology is also highly suitable for 13C isotope labeling, which was demonstrated through the synthesis of three benzoyl ureas, including the insecticide triflumuron, whereby 13CO was incorporated into the core structure.

Active agent combinations

The novel active compound combinations of extracts from seeds of the neem tree and the active compounds of groups (B) to (F) listed in the description have very good insecticidal and acaricidal properties.

Method for exterminating termites

A method for exterminating termites comprising using an entomopathogenic nematode together with an inset-growth regulator or a slow-acting insecticide, wherein insecticidal effects are reinforced compared with the cases using singly the entomopathogenic nematode and the insect-growth regulator or the slow-acting insecticide, respectively, and a bait station for exterminating termites that contains an entomopathogenic nematode with an insect-growth regulator or a slow-acting insecticide. According to the invention, emission of harmful chemicals to environment can be suppressed. The invention is nonpoisonous for human being and livestock, and is useful for indoor or outdoor extermination of termites.

Insecticidal combination to control mammal fleas, in particular fleas on cats and dogs

Process and composition, in particular for controlling fleas on small mammals, characterized in that the composition includes, on the one hand, at least one insecticide of 1-N-arylpyrazole type, in particular fipronil, and, on the other hand, at least one compound of IGR (insect growth regulator) type, in doses and proportions which are parasiticidally effective on fleas, in a fluid vehicle which is acceptable for the animal and convenient for local application to the skin, preferably localized over a small surface area.

Solid formulations

New solid formulations of A) at least one agrochemical active compound, B) at least one additive from the groups mentioned in the description, C) at least one dispersant, D) at least one carrier and E) if appropriate, further active compounds and/or additives, a process for preparing the solid formulations and their use for treating plants. A new device for preparing new granules.

Macrocyclic plant acaricides

Compounds of the formula I STR1 in which either R is methyl and there is a double bond in the 9,10-position, or in which R is hydrogen and there is a single bond in the 9,10-position, are highly active against Acarina which damage plants.

Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals

A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.

Chewing insect toxicant compositions

This invention relates to chewing insect toxicant compositions comprising (1) a 1-(mono-substituted phenyl)-3-benzoyl urea compound in admixture with (2) an amount sufficient to enhance the chewing insect toxicity of said urea compound of a phosphorous-containing compound. This invention is also directed to chewing insect toxicant compositions comprising an acceptable carrier and as the active toxicant an effective amount of the composition of this invention as well as to a method of controlling insects by subjecting them to an effective amount of the composition of this invention.