64985-85-9

Basic information

• Product Name: 2,5-Dichlorobenzoyl cyanide
• Synonyms: 2,5-dichlorobenzoyl cyanide;(2,5-Dichlorophenyl)oxoacetonitrile;2,5-Dichloro-α-oxo-benzeneacetonitrile
• CAS NO: 64985-85-9
• Molecular Formula: C₈H₃Cl₂NO
• Molecular Weight: 200.02
• EINECS: 265-298-9
• Mol File: 64985-85-9.mol

Chemical Properties

• Boiling Point: 303.9 ºC at 760 mmHg
• Flash Point: 137.6ºC
• Appearance: /
• Density: 1.446 g/cm³
• Vapor Pressure: 0.000903mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 2,5-Dichlorobenzoyl cyanide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dichlorobenzoyl cyanide(64985-85-9)
• EPA Substance Registry System: 2,5-Dichlorobenzoyl cyanide(64985-85-9)

Safety Data

• Hazardous Substances Data: 64985-85-9(Hazardous Substances Data)

Usage

Uses

2,5-Dichlorobenzoyl Cyanide is a reagent applied for research purposes

InChI:InChI=1/C8H3Cl2NO/c9-5-1-2-7(10)6(3-5)8(12)4-11/h1-3H

Upstream product

• 2905-61-5 2,5-dichlorobenzoyl chloride 
• 80277-49-2 2,5-dichlorobenzoyl fluoride 
• 18127-79-2 2,5-dichloro-benzoic acid anhydride 
• 50-79-3 2,5-dichlorobenzoic acid 

Relevant articles and documents

Regioselective synthesis of 1-substituted indazole-3-carboxylic acids

In this article, we study the synthesis of 1-substituted indazole-3-carboxylic acids from 2-halobenzoic acids.

Process for the preparation of acyl cyanides

A novel process for the preparation of acyl cyanides of the general formula wherein R represents an optionally substituted alkyl radical with 1 to 8 carbon atoms, an optionally substituted cycloalkyl radical with 3 to 12 carbon atoms, an optionally substituted aryl radical or an optionally substituted 5-membered or 6-membered heterocyclic radical, which can additionally be fused to a benzene ring, in which a carboxylic acid fluoride or the general formula in which R has the abovementioned meaning is reacted with an alkali metal cyanide, optionally in the presence of a diluent, at a temperature between 10° and 200° C. The acylcyanides (I) can be used as intermediates in the synthesis of known herbicides.

Process for the preparation of acyl cyanides

Acyl cyanides of the formula STR1 in which R represents alkyl or substituted alkyl of from 1 to 8 carbon atoms, cycloalkyl or substituted cycloalkyl of from 3 to 12 carbon atoms, aryl or substituted aryl; or an optionally substituted 5-membered or 6-membered heterocyclic radical which can also be fused with a benzene ring are prepared by reacting the corresponding carboxylic acid anhydride in the presence of a carboxylic acid halide with an alkali metal cyanide or anhydrous acid, at a temperature of between 50° and 300° C.

Process for the preparation of acyl cyanides

Acyl cyanides of the general formula STR1 in which R represents alkyl or substituted alkyl of from 1 to 8 carbon atoms; cycloalkyl or substituted cycloalkyl with 3 to 12 carbon atoms; aryl or substituted aryl; or an optionally substituted 5-membered or 6-membered heterocyclic radical which can additionally also be fused with a benzene ring, are prepared by reacting the corresponding carboxylic acid anhydride with an alkali metal cyanide or anhydrous hydrocyanic acid, at a temperature of between 50° and 250° C. and the resulting acyl cyanide is removed from the reaction medium by distillation, immediately after it has been formed.