65473-81-6

Basic information

• Product Name: Oxirane, 2-(1-methylethyl)-3-phenyl- (9CI)
• Synonyms: Oxirane, 2-(1-methylethyl)-3-phenyl- (9CI)
• CAS NO: 65473-81-6
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.22826
• Product Categories: ISOPROPYL
• Mol File: 65473-81-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Oxirane, 2-(1-methylethyl)-3-phenyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Oxirane, 2-(1-methylethyl)-3-phenyl- (9CI)(65473-81-6)
• EPA Substance Registry System: Oxirane, 2-(1-methylethyl)-3-phenyl- (9CI)(65473-81-6)

Safety Data

• Hazardous Substances Data: 65473-81-6(Hazardous Substances Data)

Upstream product

• 15325-61-8 (E)-(3-methylbut-1-en-1-yl)benzene 
• 5153-67-3 nitrostyrene 

Downstream Products

• 2893-05-2 3-methyl-1-phenylbutan-2-one 
• 4493-56-5 3-methyl-1-phenyl-butan-2-one semicarbazone 
• 611-70-1 phenyl isopropyl ketone 

Relevant articles and documents

Kinetic resolution ofN-aryl β-amino alcoholsviaasymmetric aminations of anilines

An efficient kinetic resolution ofN-aryl β-amino alcohols has been developedviaasymmetricpara-aminations of anilines with azodicarboxylates enabled by chiral phosphoric acid catalysis. Broad substrate scope and high kinetic resolution performances were afforded with this method. Control experiments supported the critical roles of the NH and OH group in these reactions.

Asymmetric epoxidation of styrene derivatives by styrene monooxygenase from Pseudomonas sp. LQ26: Effects of α- And β-substituents

Recombinant Escherichia coli expressing a styrene monooxygenase, StyAB2, from Pseudomonas sp. LQ26 was applied to synthesize a range of chiral epoxides from conjugated styrene derivatives with excellent (>99%) enantioselectivity in most cases. The substrate preference was studied with a special focus on the steric effect of α- and β-substituents.

Process for the preparation of an oxirane, azirdine or cyclopropane

A process for the preparation of an oxirane, aziridine or cyclopropane of formula (I) wherein, X is oxygen, NR4 or CHR5 ; R1 is hydrogen, alkyl, aryl, heteroaromatic, heterocyclic or cycloalkyl; R2 is hydrogen, alkyl, aryl, heteroaromatic, CO2 R8, CHR14 NHR13, heterocyclic or cycloalkyl; or R1 and R2 join together to form a cycloalkyl ring; R3 is hydrogen, alkyl, aryl, heteroaromatic, CO2 R8, R83 Sn, CONR8 R9 or trimethylsilyl; R4 and R5 are, independently, alkyl, cycloalkyl, aryl, heteroaromatic, SO2 R8, SO3 R8, COR8, CO2 R8, CONR8 R9 or CN, or R4 can also be P(O)(aryl)2 ; R8 and R9 are independently alkyl, aryl or arylalkyl; R13 and R14 are independently hydrogen, alkyl or aryl; the process comprising reacting a mixture of a compound of formula (II), wherein R1, R2 and X are as defined above, and a sulphide of formula SR6 R7, wherein R6 and R7 are independently alkyl, aryl or heteroaomatic, or R6 and R7 join together to form a cycloalkyl ring which optionally includes an additional heteroatom, with either (i) a metallocarbon obtainable by reacting an alkylmetal with a methane derivative of formula CHR3 X'X", wherein R3 is as defined above, and X' and X" are independently, a leaving group, or (ii) a metallocarbon obtainable by reacting a compound of formula (III), (wherein R3 may not be hydrogen) with a suitable organometallic or inorganic reagent.