Thiopyrano[2,3-e]indol-2-ones: Angelicin heteroanalogues with potent photoantiproliferative activity
A new class of compounds, the thiopyrano[2,3-e]indol-2-ones, bioisosters of the angular furocoumarin angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents. In particular 7,8-dimethyl-thiopyranoindolone 6c s showed a remarka
Barraja, Paola,Diana, Patrizia,Montalbano, Alessandra,Carbone, Anna,Cirrincione, Girolamo,Viola, Giampietro,Salvador, Alessia,Vedaldi, Daniela,Dall'Acqua, Francesco
experimental part
p. 9668 - 9683
(2009/04/06)
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