(AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES
Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.
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(2018/07/29)
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).
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(2015/04/15)
Indole derivatives for the treatment of depression and anxiety
The present invention provides compounds of formula (I): which are useful for treating depression, anxiety, and alleviating the symptoms caused by withdrawal or partial withdrawal from the use of tobacco or of nicotine.
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Page/Page column 38
(2010/02/05)
Substituted oxoazaheterocyclyl compounds
This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa..
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Page/Page column 68
(2008/06/13)
An improved synthesis of substituted benzo[b]thiophenes using microwave irradiation
An easy and high-yielding method for the synthesis of substituted benzo[b]thiophenes using microwave irradiation is described.
Allen, Daniel,Callaghan, Owen,Cordier, Frederic L.,Dobson, David R.,Harris, John R.,Hotten, Terry M.,Owton, W. Martin,Rathmell, Richard E.,Wood, Virginia A.
p. 9645 - 9647
(2007/10/03)
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