Decatungstate-Catalyzed C(sp3)-H Sulfinylation: Rapid Access to Diverse Organosulfur Functionality
Here we report the direct conversion of strong, aliphatic C(sp3)-H bonds into the corresponding alkyl sulfinic acids via decatungstate photocatalysis. This transformation has been applied to a diverse range of C(sp3)-rich scaffolds, including natural products and approved pharmaceuticals, providing efficient access to complex sulfur-containing products. To demonstrate the broad potential of this methodology for the divergent synthesis of pharmaceutically relevant molecules, procedures for the diversification of the sulfinic acid products into a range of medicinally relevant functional groups have been developed.
Bissonnette, Noah B.,Macmillan, David W. C.,Sarver, Patrick J.
supporting information
p. 9737 - 9743
(2021/07/19)
1-aryl ethanesulfonic acid and preparation method of its derivative
The invention provides 1-aryl ethanesulfonic acid and a preparation method of its derivative. The preparation method comprises the following steps that (a) 1-aryl halogensated ethane represented in aformula (I) and sodium hydrosulfide react to generate 1-
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Paragraph 0047-0050
(2018/04/03)
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