Synthesis of substituted tetrahydrofurans via intermolecular reactions of γ-chlorocarbanions of 3-substituted 3-chloro-propylphenyl sulfones with aldehydes
Carbanions of 3-substituted-3-chloropropyl phenyl sulfones add to carbonyl groups of aldehydes to produce aldol type adducts that undergo 1,5-intramolecular substitution giving 2,3,5-trisubstituted tetrahydrofurans. The effect of substituents in the 3-pos
Easy access to trans-2,3-disubstituted cyclobutanones, 2,4,5-trisubstituted 3,6-dihydro-2H-pyrans and cis-substituted phenylcyclopropylsulfones by using the highly versatile 1-phenylsulfenyl- or 1-phenylsulfonyl-cyclopropylketones
The high versatility of 1-phenylsulfenyl- or 1-phenylsulfonyl- cyclopropylketones has been exploited for the regioselective synthesis of trans-2,3-disubstituted cyclobutanones, 2,4,5-trisubstituted 3,6-dihydro-2H-pyrans and cis-2-alkyl- or cis-2-aryl-cycl
Alberti, Guido,Bernard, Angela M.,Floris, Costantino,Frongia, Angelo,Piras, Pier P.,Secci, Francesco,Spiga, Marco
scheme or table
p. 3512 - 3519
(2010/01/05)
Reactivity of bifunctional olefins with hydrazine hydrate - Part II
The reaction of 1-aroyl-2-arylsulfonylethenes 1 with different ratios of hydrazine hydrate lead to hydrazones, dimerized products and 2-pyrazolines. The reactivity of pyrazolines has also been studied by dehydrogenation, pyrolysis, nitrosation and acylation.
Phase transfer catalyzed cyclopropanation of trans-styryl aryl sulfones with dimethyl sulfoxonium methylide
Some new trans-aryl cyclopropyl sulfones (II) have been prepared by the cycloaddition of dimethylsulfoxonium methylide to trans-styryl aryl sulfones (I) by two different methods. It is observed that the reaction in presence of a phase transfer catalyst proceeds in a facile manner.