668276-28-6Relevant articles and documents
BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS
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Page/Page column 102; 103, (2011/02/24)
The present invention relates to benzoxazinone derivatives, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in treating disorders mediated by GlyT1, including neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder.
8-[3-Amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical composition
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Page/Page column 6, (2008/06/13)
The present invention relates to substituted xanthines of general formula wherein R1 and R2 are defined as in the claims, the tautomers, the stereoisomers, the mixtures thereof, and the salts thereof, which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
NOVEL 8-(PIPERAZINE-1-YL)- AND 8-([1,4]DIAZEPAN-1-YL)-XANTHINE, THE PRODUCTION AND USE THEREOF IN THE FROM OF A DRUG
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Page/Page column 20, (2008/06/13)
The invention relates to a substituted XANTHINE of formula (I), wherein R1 to R3 and n are such as defined in claims from 1 to 8 and tautomers, enantiomers, diastereomers, mixtures, prodrugs and the salts thereof, said substances exhibiting valuable pharmacological properties, in particular an inhibition on the activity of dipeptidylpeptidasa-IV enzyme (DPP-IV).
8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS MEDICAMENTS
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Page/Page column 18, (2008/06/13)
The invention relates to substituted xanthines of general formula (I) wherein R1 and R2 have the designations cited in patent claims 1 to 3. The invention also relates to the tautomers, stereoisomers, mixtures and salts of said xanthines, exhibiting valuable pharmacological properties, especially an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).