66855-92-3

Basic information

• Product Name: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE
• Synonyms: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE
• CAS NO: 66855-92-3
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.24328
• Mol File: 66855-92-3.mol

Chemical Properties

• Boiling Point: 367.728 °C at 760 mmHg
• Flash Point: 167.562 °C
• Appearance: /
• Density: 1.166 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE(66855-92-3)
• EPA Substance Registry System: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE(66855-92-3)

Safety Data

• Hazardous Substances Data: 66855-92-3(Hazardous Substances Data)

Usage

Uses

Used in Fragrance and Flavor Industry:
3-(2-Methoxy-phenoxy)-benzaldehyde is utilized as a key ingredient in the fragrance and flavor industry due to its sweet, floral scent. Its aromatic properties make it suitable for incorporation into a wide range of products, including perfumes, colognes, and food flavorings.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 3-(2-Methoxy-phenoxy)-benzaldehyde serves as a valuable intermediate for the synthesis of various medicinal compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
3-(2-Methoxy-phenoxy)-benzaldehyde is employed as a versatile building block in organic synthesis. Its chemical properties make it an ideal candidate for the creation of complex molecules, which can be used in a variety of applications, such as the development of new materials, dyes, and other specialty chemicals.

InChI:InChI=1/C14H12O3/c1-16-13-7-2-3-8-14(13)17-12-6-4-5-11(9-12)10-15/h2-10H,1H3

Upstream product

• 87199-16-4 3-Formylphenylboronic acid 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 912461-49-5 tert-butyl 9-[3-(2-methoxyphenoxy)benzyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate 
• 1179356-28-5 3-[3-(2-methoxyphenoxy)benzyl]-9-(pyrimidin-4-ylcarbonyl)-3,9-diazaspiro[5.5]undecane trifluoroacetate 
• 521975-55-3 tert-butyl-4-((1-(3-(2-methoxyphenoxy)benzyl)piperidin-4-yl)carbamoyl)-4-phenylpiperidine-1-carboxylate 
• 889654-14-2 4-amino-1-[3-(2-methoxyphenoxy)benzyl]piperidine-4-carboxylic acid methyl ester 

Relevant articles and documents

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Activation of CCR8 by its ligand CCL1 may play an important role in diseases such as asthma, multiple sclerosis, and cancer. The study of small molecule CCR8 antagonists will help establish the validation of these hypotheses. We report the design, synthesis, and progress toward optimization of potent small molecule CCR8 antagonists identified from a high-throughput screen. These analogues exhibit good potency in binding and chemotaxis assays, show good selectivity versus the hERG channel, and have good eADME (early absorption, distribution, metabolism, and excretion) profiles.

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The invention provides compounds of general formula. [Chemical formula should be inserted here. Please see paper copy] (II) wherein R and R1 are as defined in the specification, processes for their preparation, pharmaceutical compositions conta

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The invention provides compounds of general formula wherein R and R1 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

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The invention provides compounds of general formula. (II) wherein R and R?1? are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.